27 of 41 Mutations in two important cancer-critical genes, encoding p53 and Rb, respectively, are commonly found in cancers. What type of mutations are these expected to be? O Gain-of-function mutation in p53 and loss-of-function mutation in Rb O Loss-of-function mutation in p53 and gain-of-function mutation in Rb O Loss-of-function mutations in both genes O Gain-of-function mutations in both genes

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter12: Genes And Cancer
Section: Chapter Questions
Problem 15QP: Which of the following mutations will result in cancer? a. homozygous recessive mutation in a...
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27 of 41
Mutations in two important cancer-critical genes, encoding p53 and Rb, respectively, are commonly found in cancers. What type of mutations are these expected to be?
O Gain-of-function mutation in p53 and loss-of-function mutation in Rb
O Loss-of-function mutation in p53 and gain-of-function mutation in Rb
O Loss-of-function mutations in both genes
O Gain-of-function mutations in both genes
Transcribed Image Text:27 of 41 Mutations in two important cancer-critical genes, encoding p53 and Rb, respectively, are commonly found in cancers. What type of mutations are these expected to be? O Gain-of-function mutation in p53 and loss-of-function mutation in Rb O Loss-of-function mutation in p53 and gain-of-function mutation in Rb O Loss-of-function mutations in both genes O Gain-of-function mutations in both genes
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