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- GTP or ATP is produced during the conversion of isocitrate into ketoglutarate succinyl CoA into succinate fumarate into malate malate into oxaloacetateIf phenylalanine was not an essential amino acid, would diet therapy (the elimination of phenylalanine from the diet) for PKU work?The Reactions and Meehanisms of the Leloir Pathway Write the reactions that permit galactose to be utilized in glycolysis. Write a suitable mechanism, tor one of these reactions.
- Using the ActiveModel for aldose reductase, describe the structure of the TIM barrel motif and the structure and location of the active site.Psilocybin is a hallucinogenic compound found in some mushrooms. Present a straightforward pathway for its biosynthesis from one of the aromatic amino acids.Unbranched homopolymer of N-acetyl glucosamine is : 1.Cellulose 2.Chitin 3.Curcumin 4.Concanavalin A
- Talose is the C4 epimer of mannose.draw the chair conformation of D-talopyranoseWhy should phenylketonurics avoid using aspartame, an artificial sweetener? (Hint: Aspartame is Laspartyl-L-phenylalanine methyl ester.)Briefly describe the function of uridine triphosphate (UTP) in carbohydratemetabolism.
- Bovine chymotrypsinogen has a molecular massof 25.6 kDa. Amino acid analysis shows that thisenzyme is 4.7% Gly (Mr 75.1).b. Calculate how many glycine residues are present in amolecule of bovine chymotrypsinogenThe key regulatory enzyme in pyrimidine synthesis is: a. Aspartate transcarbamoylase. b. Glutamine phosphoribosyl amidotransferase. c. Uridine monophosphate synthetase. d. Orotidylate decarboxylaseSalicylamides are inhibitors for an enzyme called scytalone dehydratase. SAR shows that there are three important hydrogen bonding interactions. Explain whether you think quinazolines could act as a bioisostere for salicylamides.
