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3. When the hormone vasopressin stimulates cleavage of phosphatidylinositol 4,5-bisphophate (PIP2) by phospholipase C, two products are formed. a) The structure of inositol is shown at right. Use your knowledge of naming conventions to determine the structure of PIP2. Explain in HO complete sentences which groups would be attached to this inositol in phosphatidylinositol 4,5-bisphophate (PIP2). OH HOW HO O., он b) Given the information below and your knowledge of glycerophospholipids, what are the two products of cleavage by phospholipase C? Phospholipase Site of cleavage A1 Ester bond at C-1 of glycerol Ester bond at C-2 of glycerol Phosphodiester bond at C-3 of glycerol Phosphodiester bond between phosphate and head group A2 c) Compare the properties and solubility of these two products. Predict whether either would diffuse readily through the cytosol.

3. When the hormone vasopressin stimulates cleavage of phosphatidylinositol 4,5-bisphophate (PIP2) by phospholipase C, two products are formed. a) The structure of inositol is shown at right. Use your knowledge of naming conventions to determine the structure of PIP2. Explain in HO complete sentences which groups would be attached to this inositol in phosphatidylinositol 4,5-bisphophate (PIP2). OH HOW HO O., он b) Given the information below and your knowledge of glycerophospholipids, what are the two products of cleavage by phospholipase C? Phospholipase Site of cleavage A1 Ester bond at C-1 of glycerol Ester bond at C-2 of glycerol Phosphodiester bond at C-3 of glycerol Phosphodiester bond between phosphate and head group A2 c) Compare the properties and solubility of these two products. Predict whether either would diffuse readily through the cytosol.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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biochemistry
3. When the hormone vasopressin stimulates cleavage of phosphatidylinositol 4,5-bisphophate (PIP2) by phospholipase C, two products are formed. a) The structure of inositol is shown at right. Use your knowledge of naming conventions to determine the structure of PIP2. Explain in HO complete sentences which groups would be attached to this inositol in phosphatidylinositol 4,5-bisphophate (PIP2). OH HOW HO" "HO, OH b) Given the information below and your knowledge of glycerophospholipids, what are the two products of cleavage by phospholipase C? Phospholipase Site of cleavage Ester bond at C-1 of glycerol Ester bond at C-2 of glycerol Phosphodiester bond at C-3 of glycerol Phosphodiester bond between phosphate and head group A1 A2 C c) Compare the properties and solubility of these two products. Predict whether either would diffuse readily through the cytosol.
Transcribed Image Text:3. When the hormone vasopressin stimulates cleavage of phosphatidylinositol 4,5-bisphophate (PIP2) by phospholipase C, two products are formed. a) The structure of inositol is shown at right. Use your knowledge of naming conventions to determine the structure of PIP2. Explain in HO complete sentences which groups would be attached to this inositol in phosphatidylinositol 4,5-bisphophate (PIP2). OH HOW HO" "HO, OH b) Given the information below and your knowledge of glycerophospholipids, what are the two products of cleavage by phospholipase C? Phospholipase Site of cleavage Ester bond at C-1 of glycerol Ester bond at C-2 of glycerol Phosphodiester bond at C-3 of glycerol Phosphodiester bond between phosphate and head group A1 A2 C c) Compare the properties and solubility of these two products. Predict whether either would diffuse readily through the cytosol.
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