
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Question
I need question 38

Transcribed Image Text:31. In each example below, what will be the result after replication if not repaired? Also note if it results in a
transition or transversion:
a.
O pase pair, an adenine tautomer is placed across from the cytosine during replication
ma 1:A base pair, the adenine undergoes tautomerization prior to replication
na TA base pair, 5-bromouracil is incorporated across from an adenine prior to replication
d. in an A:T base pair, oxoG is placed across from the A during replication
C.
Why is MutT so important? What occurs in cells lacking this enzyme?
o. How does DNA polymerase proofreading specifically recognize mispairs (by what mechanism)?
34. Define the roles of each in mismatch repair: MutS, MutL, and MutH, exonuclease
35. How does E. coli distinguish between the old and new strand for mismatch repair?
36. How do human cells distinguish between the old and new strand for mismatch repair?
37. What are the steps of base excision repair? Where does the glycosylase cleave?
38. Why does the OxoG failsafe system lead to more ATD CG than CGD@ẠT transversions?
39. What are the steps of nucleotide excision repair in bacteria? Why are the bacterial proteins in this pathway
named "UV" and human proteins "XP"?
40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed by
RNA polymerase quickly?
41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair ssDNA or
dsDNA?
12. What are the steps of homologous recombination repair? Which proteins are involved in searching for
homologous sequences and how do they function?
B. What are the steps of nonhomologous end joining?
When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair ssDNA or dsDNA?
Describe the general steps needed for a cell to become cancerous.
How do mutations and chromosomal abnormalities affect proteins and lead to disease?
What role do cell cycle checkpoints have in cancer?
Define a tumor suppressor and oncogené and give an example of ea
Define the role of ATM in the cell and cancer. UporyDNA damage, ATM decides whether to activațe HRR or
wnigh
Which is preferred and why?
Expert Solution

This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution
Trending nowThis is a popular solution!
Step by stepSolved in 3 steps with 1 images

Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- i need the answer quicklyarrow_forward3r0 degree Question 66 U UUU UUC UUA UUG CUU CUC CUA CUG Phe AUU Lou GUU GUC GUA GUG HELP CENTER Leu Arg C UCU- UCC UCA UCG- ACU- AUC ACC AUA ACA Met or AUG Start ACG SECOND BASE CCU CCC CCA CCO -Val acu- acc Ser GCA aca Question 67 G UGU-1 UGC UAA Stop UGA Stop A UAG SUGG Trp G UAU UAC Pro Thr A CAU CAC CAA CAG Ala -Tyr -His AAU- AAC- AAA- AAG GAU GAC GAA GAG -Gin Asn -Lve Lys CGU CGC CGA coa -Asp -Glu AGU AGC AGA AGG -Cys GOU GGC GGA GGG U Arg U Ic -Ser Arg Gly A U С 4 Use the chart to find the amino acid that the DNA triplet AGG codes for. Write the 3 letter abbreviation for the correct amino acid. Full thickness burn tharrow_forwardQuestion 52 In women, laparoscopy would be used to diagnose and /or remove all but O Fibroids O cervical polyps ovarian cysts adhesions lages may not show up) - use Chr << Previous Nearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education

Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON

Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax

Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,

Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company

Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.

Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education