A physician diagnoses an infant patient with a pyruvate carboxylase deficiency in part by measuring the patient's blood levels of lactate and pyruvate. How would the patient's [lactate)/[pyruvate] ratio compare to the ratio in a normal infant? The patient's [lactate)/[pyruvate] ratio would be less than the ratio in a normal infant. The patient's [lactate/[pyruvate] ratio would be the same ratio in a normal infant. The patient's (lactate)/[pyruvate] ratio would be greater than the ratio in a normal infant. eTextbook and Media Anormal patient injected with alanine would experience in blood glucose, as the injected alanine enters the liver and becomes a substrate for gluconeogenesis. The glucose produced leaves the liver and * blood glucose concentration. The blood glucose enters the bloodstream, which accounts for the concentration of the patient with a pyruvate carboxylase deficiency would * .The injected alanine would be successfully converted to pyruvate, but the gluconeogenic pathway could further in the absence of pyruvate carboxylase.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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A physician diagnoses an infant patient with a pyruvate carboxylase deficiency in part by measuring the patient's
blood levels of lactate and pyruvate.
How would the patient's [lactate]/[pyruvate] ratio compare to the ratio in a normal infant?
The patient's [lactate/[pyruvate] ratio would be less than the ratio in a normal infant.
The patient's (lactate)/[pyruvate] ratio would be the same ratio in a normal infant.
The patient's (lactate/[pyruvate] ratio would be greater than the ratio in a normal infant.
eTextbook and Media
* in blood glucose, as the injected
Anormal patient injected with alanine would experience
alanine enters the liver and becomes a substrate for gluconeogenesis. The glucose produced leaves the liver and
* blood glucose concentration. The blood glucose
enters the bloodstream, which accounts for the
* .The injected
concentration of the patient with a pyruvate carboxylase deficiency would
alanine would be successfully converted to pyruvate, but the gluconeogenic pathway could
further in the absence of pyruvate carboxylase.
Transcribed Image Text:A physician diagnoses an infant patient with a pyruvate carboxylase deficiency in part by measuring the patient's blood levels of lactate and pyruvate. How would the patient's [lactate]/[pyruvate] ratio compare to the ratio in a normal infant? The patient's [lactate/[pyruvate] ratio would be less than the ratio in a normal infant. The patient's (lactate)/[pyruvate] ratio would be the same ratio in a normal infant. The patient's (lactate/[pyruvate] ratio would be greater than the ratio in a normal infant. eTextbook and Media * in blood glucose, as the injected Anormal patient injected with alanine would experience alanine enters the liver and becomes a substrate for gluconeogenesis. The glucose produced leaves the liver and * blood glucose concentration. The blood glucose enters the bloodstream, which accounts for the * .The injected concentration of the patient with a pyruvate carboxylase deficiency would alanine would be successfully converted to pyruvate, but the gluconeogenic pathway could further in the absence of pyruvate carboxylase.
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