A scientist observes a mutation in the transmembrane region of EGFR that eliminates its ability to be stabilized by binding interactions during dimerization after ligand binding. Which hypothesis regarding the effect of this mutation on EGF signaling is most likely to be correct? a. EGF signaling cascades would be active for longer in the cell. b. EGF signaling cascades would be active for a shorter period of time in the cell. c. EGF signaling cascades would not occur. d. EGF signaling would be unaffected.
A scientist observes a mutation in the transmembrane region of EGFR that eliminates its ability to be stabilized by binding interactions during dimerization after ligand binding. Which hypothesis regarding the effect of this mutation on EGF signaling is most likely to be correct? a. EGF signaling cascades would be active for longer in the cell. b. EGF signaling cascades would be active for a shorter period of time in the cell. c. EGF signaling cascades would not occur. d. EGF signaling would be unaffected.
Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter6: Cell Communication
Section: Chapter Questions
Problem 8TYU: Scaffold proteins (a) release kinases and phosphatases into the extracellular fluid (b) bind G...
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Question
A scientist observes a mutation in the transmembrane
region of EGFR that eliminates its ability to be stabilized
by binding interactions during dimerization after ligand
binding. Which hypothesis regarding the effect of this
mutation on EGF signaling is most likely to be correct?
a. EGF signaling cascades would be active for longer
in the cell.
b. EGF signaling cascades would be active for a
shorter period of time in the cell.
c. EGF signaling cascades would not occur.
d. EGF signaling would be unaffected.
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