appears quite suddenly. How would we best explain the rapid activation of cyclin-Cdk? a. Cyclin-Cdk gene expression leads to rapid protein synthesis. b. All cyclin-Cdk is activated when it exits the nucleus. c. Ubiquination leads to proteolytic activation of the cyclin. d. Positive feedback loops cause its rapid activation. G1 S G2 M

appears quite suddenly. How would we best explain the rapid activation of cyclin-Cdk? a. Cyclin-Cdk gene expression leads to rapid protein synthesis. b. All cyclin-Cdk is activated when it exits the nucleus. c. Ubiquination leads to proteolytic activation of the cyclin. d. Positive feedback loops cause its rapid activation. G1 S G2 M

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter10: Cell Division And Mitosis

Section: Chapter Questions

Problem 8TYK: Which of the following statements about cell cycle regulators is incorrect? a. The concentrations of...

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Which of the following statements about cell cycle regulators is incorrect? a. The concentrations of cyclins change throughout the cell cycle. b. Cyclins are present in all stages of the cell cycle except S. c. Cyclin-Cdk complexes phosphorylate target proteins. d. Cdks combine with cyclin to move the cycle into mitosis. e. During anaphase of mitosis, cyclin is degraded, allowing mitosis to end.
1.The cells of cancerous tumors undergo changes that cause them to bear little to no resemblance to their original cell type. Predict how this will affect the ability of thise cells to perform thier function. A. Increased growth in the thickness in the alveolar tissue of lungs can allow fir more oxygen and can be detrimental if too much gas exchange occurs. B. Increase in abnormal growth in compact bone tissue can cause bones to become stronger. C. Tumor in the bladder can lead to the disproportionate growth of the epithelial tissue that allows the bladder to stretch; therefore, it will create a constant urgency to urinate. D. All choices are correct (I think it's between A and C but not sure which one)
With regard to cancer cells, which of the following statementsare true?A. Cancer cells are clonal, which means they are derived from asingle mutant cell.B. To become cancerous, cells usually accumulate multiplegenetic changes that eventually result in uncontrolledgrowth.C. Most cancers are caused by oncogenic viruses.D. Cancer cells have lost the ability to properly regulate celldivision.
3. Which of the following types of mutations would NOT be advantageous to a cancer cell? a.An inactivating mutation in pRb b.An inactivating mutation in a gene controlling a DNA damage checkpoint c.An inactivating mutation in p16INK4A d.An inactivating mutation in cyclin D e.An inactivating mutation in p19INK4D
8. Molecules outside and inside the cell regulate the cellcycle, making it start or stop.a. What is an example of an external molecule thatregulates the cell cycle?b. What is an example of a molecule inside the cellthat is involved in cell-cycle regulation?
An active S-cdk (a type of CDK) will most likely _________ a. degrade cyclin b. promote apoptosis c. prevent the cell cycle d. promote the cell cycle e. prevent apoptosis
What statement about Cdks/Cyclins below is false? A) Cyclins phosphorylate Cdks B) Cdks are kinases C) Cdk expression is constant during the cell cycle D) Cyclin expression fluctuates during the cell cycle E) Cdk activity fluctuates during the cell cycle
1. A brief intrwhich introduces ALP as a diagnostic tool in cancer and create a Graphical Abstract to summarise the role of ALP in cancer?
2. Characterize the differences between tumor cells andnormal cells in terms of the following properties. Incancer cells, how might each of these propertiescontribute to tumor progression?a. contact inhibitionb. autocrine stimulationc. apoptosisd. telomerase expressione. senescence due to telomere shortening
1. Which organelles is the main calcium store for signaling? Lyosome; ER; Golgi; secretary vesicles 2. A temperature sensitive mutant yeast strains/stops dividing when shifted from. 25 degrees Celsius to 37 degrees Celsius. These cells are analyzed at different temperatures by a machine that measures the amount of DNA they contain. What would explain the behavior of the mutant? Anaphase promoting complex is inactivatend; s cdk is inactivated; m cdk is inactivate; m cycling is overexposed 3.which of the following statements about proto oncogenes is true? Proto oncogenes inhibit cell growth and division; cancer cells often contain loss of function mutations in proto oncogenes; proto oncogenes are needed for cells in normal tissues; none 4. Which of the following statements about tumor suppressor genes is true? Gene amplification of a tumor suppressor gene is more dangerous than gene amplification of a proto oncogenes; tumor suppressor genes are more highly expressed in cancer cells…
f you are growing mammalian cells in culture that are in G0, which of the following would you add to the cell culture media to stimulate them to leave G0 and enter the cell cycle? A. growth factors or other growth stimulatory molecules B. Taq polymerase C. Tau D. BrdU E. Na+ ions
1.Colchicine is a type of drug that inhibits the microtubule formation during the cell division. Let’s say that the onion root tip (a place where most of the plant’s cells divide) was submerge in colchicine solution. a. How do you think will be the cell’s respond? Will it continue its cell division? Why or why not? b. Let’s say that the cells in onion root tip treated with colchicine were not halted at spindle checkpoint. What do you think will happen during the division?