Chi-square is a statistical test comparing a set of observed data against expected data to check for goodness-of-fit that can be used to analyze genetic crossing outcome. What is the null hypothesis for the chi-square analysis? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a b C d The null hypothesis suggests the data will not follow Mendelian inheritance. The null hypothesis is based on the concept of their being no difference between the observed values and the expected values. The null hypothesis is based on the concept of blending of traits. The null hypothesis is always the value 100%.

Chi-square is a statistical test comparing a set of observed data against expected data to check for goodness-of-fit that can be used to analyze genetic crossing outcome. What is the null hypothesis for the chi-square analysis? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a b C d The null hypothesis suggests the data will not follow Mendelian inheritance. The null hypothesis is based on the concept of their being no difference between the observed values and the expected values. The null hypothesis is based on the concept of blending of traits. The null hypothesis is always the value 100%.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter5: The Inheritance Of Complex Traits

Section: Chapter Questions

Problem 2QP: The text outlines some of the problems Frederick William I encountered in his attempt to breed tall...

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Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?
Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?
Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?
You have been hired to produce a family tree for three generations of a family where a disorder called “blinky” syndrome is observed. People who suffer from blinky syndrome blink their eyes rapidly when they look at bright lights. In order to draw a pedigree chart for this family, you interview Mike and Annie. Neither suffer from this syndrome. Annie’s mother is normal, while Annie’s father blinked like crazy at bright lights. Annie has one sister and one brother and both of them are unaffected. While Annie’s sister has yet to have kids, her brother married a blinky sufferer. Mike’s mother is a blinker while his father is normal. Mike’s brother is just like their mother. In addition, this brother married a blinker. Mike’s sister is normal - as is her husband and their one boy. Draw a pedigree chart below in order to answer the following on the next page. Use the letters A and a for the genotypes. If more than one genotype is possible for an individual - you may write it as A with a…
You have been hired to produce a family tree for three generations of a family where a disorder called “blinky” syndrome is observed. People who suffer from blinky syndrome blink their eyes rapidly when they look at bright lights. In order to draw a pedigree chart for this family, you interview Mike and Annie. Neither suffer from this syndrome. Annie’s mother is normal, while Annie’s father blinked like crazy at bright lights. Annie has one sister and one brother and both of them are unaffected. While Annie’s sister has yet to have kids, her brother married a blinky sufferer. Mike’s mother is a blinker while his father is normal. Mike’s brother is just like their mother. In addition, this brother married a blinker. Mike’s sister is normal - as is her husband and their one boy. Draw a pedigree chart below in order to answer the following on the next page. Use the letters A and a for the genotypes. If more than one genotype is possible for an individual - you may write it as A with a…
Lorenzo has a double row of eyelashes (MIM 126300) which he inherited from his mother as a dominant trait. His maternal grandfather is the only other relative to have it. Fatima, who has normal eyelashes, marries Lorenzo. The first child, Nicola (girl) has normal eyelashes. Now Fatima is pregnant again and hopes for a child with double eyelashes. What chance does the child have of inheriting double eyelashes? Draw a pedigree of this family.
Over the years, Mendel experimented with more than 30,000 pea plants. Why did Mendel collect data on so many plants? Why didn’t he study just one cross? Hint: Read “What Are the Odds?” on page 124 before answering.
For the trait being followed in the pedigree, individuals II-1 and II-4 in Figure 12-1 can be classified as _____.
Make a pedigree analysis on a five generation family using both maternal and paternal side. (great great grandparents as generation 1) All have a light brown skin color and straight hair. Use attached photo as a reference. (All names with highlighted yellow color are female. The rest are male. Name with red is deceased person. Name with green color are their spouse. Name with underline is the 5th gen (kids) )
Ben, Marie, and Korra are siblings. Ben is blood type O, Anna is blood type B, and Kora is type A. What could be the possible genotype of their parents? a. |A |A and |B b. |A |A and |B |B c. |B and |A d. |A and |B |B
A young couple went to see a genetic counselor because each had a sibling with cystic fibrosis. (Cysticfibrosis is a recessive disease, and neither member ofthe couple nor any of their four parents is affected.)a. What is the probability that the female of thiscouple is a carrier?b. What are the chances that their child will havecystic fibrosis?c. What is the probability that their child will be acarrier of the cystic fibrosis disease allele?
Choose the correct choice for each blank. The parentheses represent the choices for each blank. In a pedigree, the relationships between individual family members are represented as ___________(circles and squares, lines). Individuals who have the studied trait are represented by __________ (open shapes, filled shapes)