Different control mechanisms are used to regulate the synthesis of glycogen. Match the action on the left with the effect on the right. Increase in the concentration of inorganic phosphate ion Decrease in the activity of phosphoprotein phosphatase Phosphorylation of glycogen phosphorylase Dephosphorylation of glycogen synthase Ű Clear All Decreasing glycogen synthesis Increasing glycogen synthesis No effect on glycogen synthesis
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- Discuss the roles of phospholipase A2, cyclooxygenase, and lipooxygenase.Glycogen synthase may be regulated by covalent modification and/or allosteric control. Label the diagram with the appropriate terms to describe glycogen synthase regulation. Use the following options: Glucose-6-Phospate; Insulin; Fructose-2,6-Bisphosphate; Phosphorylation, DephosphorylationIn order for a fatty acid stored in an adipocyte to be oxidized by a muscle cell, which of the following will need to be present/utilized? Check all that apply. Multiple answers can be selected Acyl CoA Synthetase CD36 malate-aspartate shuttle dephosphorylated hormone-sensitive lipase GLUT 4
- Which of the following is true for role of glucose-6-phosphate in the regulation of carbohydrate metabolism? -Glucose-6-phosphate allosterically activates glycogen phosphorylase -Glucose-6-phosphate allosterically inhibits glycogen synthase -Glucose-6-phosphate allosterically inhibits hexokinase kinase -None of the above are correct For a reaction A + B --> C + D, [A] is 0.1M, [B] is 0.1M, [C] is 0.1M, and [D] is 0.1M. which of thefollowing is true? -It is a near-equilibrium reaction -The standard free energy change equals 0.00 -The equilibrium constant equals 1.00 -Mass action ratio equals 1.00Select the following enzymes that utilize a mechanism where ATP serves as the phosphate donor. Select ALL that apply: a) glyceraldehyde 3 phosphate dehydrogenase b) hexokinase c) aldolase class 1 d) PFK e) phosphoglucoisomeraseCHOOSE THE CORRECT LETTER When glycogen is synthesized in both the liver and muscle, all the following are true, EXCEPT A.Glucose is transferred from UDP-glucose to a growing glycogen molecule by glycogen synthase.B. Phosphoglucomutase converts glucose 6-phosphate to glucose 1-phosphateC. Glucose 6-phosphate is converted to glucose by a phosphatase.D.Glucose 1-phosphate is activated by UDP-glucose pyrophosphorylase to produce UDP-glucose and PPi.
- If the brain needs glucose, then gluconeogenesis stops after reaction (9, 8, 10, 2) because (phosphoenolpyruvate, glucose, glucose-6-phosphaet, fructose-6-phosphate) can be exported from the hepatocyte using a transporter.The synthesis and degradation of glycogen in muscle is not a futile (ATP-hydrolyzing)cycle because:A. glycogen synthase and phosphorylase are simultaneously activatedB. cyclic AMP activates adenylate kinase. C. when glycogen synthase is inactivated, phosphorylase is simultaneously activated. D. glycogen binds Mg2+, thereby lowering the concentration of MgATP2-Indicate what will happen ( increase, decrease or no effect) tothe activity of the enzyme or rate of the metabolic pathway in the given conditions a. release of glucagon in the blood to the activity of carnitine acyl transferase 1 b. high malonyl CoA to the activity of carnitine acyl transferase I C. Epinephrine to the activity og glycogen synthase d. high citrate to the activity of acetyl CoA carboxylase e. high acetyl CoA to ketogenesis
- in triacylglycerol mobilization, triacylglycerol molecules is activated by: phosphorylation hydrolysis reduction oxidationIndividuals with Pompe disease lack the lysosomal _______. a. Glycogen phosphorylase b. Amylo-α(1→6)-glucosidase c. α(1→4)-glucosidase d. Glucose-6-phosphataseWhich of these enzymes/complexes will insulin activate in the liver? Choose all that apply. Glycogen synthase Glycogen phosphorylase Acetyl-CoA carboxylase Carnitine shuttle PFK-1 FBPase-1