Ethidium Bromide is a chemical reagent that has been used to detect the presence of nucleic acids. It is known to fluoresce under UV light and the intensity of the fluoresence increases when it binds to the nucleic acids. Ethidium Bromide binds to polynucleotides  a   by binding directly to the bases on one of the strands. b   by intercalating itself between the base pair stacks. c   through the negatively charged phosphate groups. d   through the hydroxyl group of the sugar molecule.

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter8: The Structure, Replication, And Chromosomal Organization Of Dna
Section: Chapter Questions
Problem 17QP: Chemical analysis shows that a nucleic acid sample contains A, U, C, and G. Is this DNA or RNA? Why?
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Ethidium Bromide is a chemical reagent that has been used to detect the presence of nucleic acids. It is known to fluoresce under UV light and the intensity of the fluoresence increases when it binds to the nucleic acids. Ethidium Bromide binds to polynucleotides 

a  

by binding directly to the bases on one of the strands.

b  

by intercalating itself between the base pair stacks.

c  

through the negatively charged phosphate groups.

d  

through the hydroxyl group of the sugar molecule.

 

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