examine the process of gene expression. Include the following: Explain the regulation of gene expression in eukaryotic cells. Discuss mechanisms by which gene expression may be altered. How do these alterations induce cancer-causing mutations in cell DNA? Explain how cancer is formed. Describe genetic changes found in cancer cells and how these changes lead to alterations in cell behavior. Determine whether proteome data can be utilized in genetic disorder diagnosis. Relate the Human Genome Project data to the analysis of cancer genes. Relates the Human Genome Project's utility in pharmacogenomics and personalized medicine to diagnose and treat cancer

Q: How can the role of epigenetics in cancer be reconciled with the idea that cancer is caused by the…

A: Epigenetics is the study of various alterations in an organism occurred because of certain gene…

Q: Define tumor-suppressor genes. Why is a mutated single copy of a tumor-suppressor gene expected to…

A: The repeated and uncontrollable division of cells forms a large mass called the tumor. Tumors might…

Q: Explain how p53 functions as a tumor suppressor gene. How can mutations in p53 lead to cancer, and…

A: Normal cell has low level of p53 protein. When DNA damage or other stress signals may trigger p53…

Q: Why are people more likely to develop cancer as they age? Why does inheriting a mutation increase…

A: Cancer is the name given to a collection of related diseases.In all types of cancer,some of the…

Q: Explain how mutations in tumor-suppressor genes can be recessive at the level of the cell but cause…

A: A tumor suppressor gene is normally a cellular gene that regulates the cell proliferation or DNA…

Q: Discuss the complete cell cycle in a human cell, mitosis and meiosis, and the regulatory components…

A: There are two types of cell division.They are Mitosis and Meiosis. Most of the times,the type of…

Q: The p53 gene encodes a tumor-suppressor protein, p53, which acts as a transcription factor for…

A: Answer. Genes for which a gain of function mutation drives a cell towards cancer are called proto…

Q: Explain how Epigenetics are related with Cancer ?

A: Answer- Epigenetics is the change in the gene expression without changing the sequence of the DNA.

Q: Explain how mutations in oncogenes and in tumor suppressorgenes cause cancer.

A: Cancer is a group of diseases that involves abnormal growth of the cell. These cells have the…

Q: Define tumor-suppressor genes. Why is a mutation in a single copy of a tumor-suppressor gene…

A: Tumor-supressor genes: Tumor-suppressor genes is defined as normal genes that will slow down the…

Q: Describe the genetic changes that inactivate tumor-suppressor genes.

A: Cancer is a condition of uncontrolled cell division which results in the formation of tumor. This is…

Q: Discuss how oncogenes and tumor suppressor genes are related to genes involved in the control of…

A: Tumor suppressor genes are the regular genes present in the genome which are important for the…

Q: Compare and contrast oncogenes and tumor suppressor genes.

A: Oncogenes are those genes that have the potential to cause cancer. These genes are often mutated or…

Q: How can a mutation in a tumor-suppressor gene contribute to the development of cancer?

A: Tumor-suppressor genes are like any other normal genes whose functions include slowing down cell…

Q: Explain about the Cancer-causing gene formed by a mutation in a proto-oncogene ?

A: In genetics, the mutation is defined as the changes or alteration in the DNA sequences which result…

Q: Cancer is caused by many different types of gene mutations. Some mutations are in proto-oncogenes,…

A: Cells split into new cells so that the body uses them and cancer starts with this wonderful…

Q: illustrate some of the molecular mechanisms leading from loss-of-function mutations in…

A: Tumor suppressing genes also known as Anti - oncogenes are the  regulatory genes which regulates…

Q: Discuss the interplay between genetics and environment in the development of cancer (it would be…

A: Research on several diseases have found that the cause of diseases are not only environmental or…

Q: explain which controls over gene expression are likely to be very brief, which may be long lasting,…

A: DNA and RNA are the types of nucleic acids that carry genetic information. DNA is transcribed to…

Q: Describe cancer cell types and the differentiation process that occurs during cancer development.

A: Cancer cells are very notorious for causing high Morbidity and mortality among patients of various…

Q: The effects of DNA mutations within the p53 gene on the structure and function of the protein…

A: The TP53 gene provides instructions for making a protein called tumor protein p53. This protein acts…

Q: Describe the differences between point mutations, chromosomal translocations, and gene amplification…

A: Cancer is a disease that is associated with the uncontrolled division of cells and invasion of…

Q: Mutations in proto-oncogenes that turn them into oncogenes tend to be dominant, while cancer-causing…

A: Tumor suppressor genes are the genes that suppress the formation of tumors in the cells or tissues…

Q: Describe the underlying causes of epigenetic changes associated with cancer.

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Select the statements that accurately describe different ways that translocations could lead to…

A: Answer-  (A) A translocation breaks up the sequence of a gene for a protein that stimulates…

Q: relationship that may exist between mutations and cancer

A: Any permanent change occurring in the DNA base sequence is referred to as a mutation. The mutation…

Q: Describe the effects of the mutation causing the p21 promoter to no longer bind p53 on cell…

A: p53 is a tumor suppressor gene but if p53 gets mutated then this protein is not able to bind to the…

Q: Explain the Role of telomere in regards to cancer

A: Telomeres gradually shorten with each cell division, resulting in less protection for the…

Q: xplain the molecular mechanisms of cancers caused by a P53 gene mutation.

A: cancer may be a disease during which a number of the body’s cells grow uncontrollably and spread to…

Q: Define oncogene, proto-oncogene, and tumor-suppressor gene.

A: The most common gene in people with cancer is p53 or TP53. More than 50% of cancers involve the lost…

Q: Explain the difference between proto-oncogene and tumor suppressor mutations in terms of its…

A: Cancer is a medical condition that is characterized by the growth of tumors in the body of an…

Q: Please distinguish driver and passenger mutations in cancer.

A: Driver mutations: Mutations in known oncogenes that help cells establish or maintain the transformed…

Q: Which of the following chromosomal changes would be LEAST likely to cause the development of cancer?…

A: Cancer is a condition where cells in a specific part of the body grow and reproduce uncontrollably.…

Q: What types of evidence indicate that cancer arises from genetic changes?

A: Cancer is a disorder in which abnormal cells divide irrepressibly and destroy the tissues of the…

Q: Sequencing the human genome, the development of microarray technology, and personal genomics promise…

A: To describe: How are Sequencing the human genome, the development of microarray technology, and…

Q: Apart from p53, mention and describe the function of three tumor suppressor genes you know

A: The cancer related genes can be divided into two broad categories like the proto-oncogenes and tumor…

Q: Discuss the relationship between genes and phenotype in terms of gene expression and the symptoms…

A: Units of inheritance are called genes. Genes are the DNA regions that encode proteins. Each gene…

Q: EXPLAIN BRIEFLY: Explain the molecular mechanisms of cancers caused by a P53 gene mutation.

A: Answers P53 also defined as tumour suppressor Gene. Hence it protect the cells from various damages…

Q: If a mutation occurs in an embryonic stem cell that alters cell proliferation there is potential for…

A: Stem cells are undifferentiated cells that have potential to develop many different types of cells…

Q: help!!! Answer the following questions Only in cell biology 1. A. Discuss the roles of two main…

A: Stem cells are reserve cells that involve in the growth and differentiation of tissues. It has the…

Q: How may genes play a role in the susceptibility of inheriting cancers? The reproductive system…

A: Cancer is a disease in which the body's cells grow out of control and spread to other tissues. Any…

Q: Explain about Regulation of gene expression.

A: Introduction There are two key components which help in gene regulation Activators Repressors The…

Q: What is the role of regulatory gene mutations in cancer?

A: Regulatory genes are defined as genes which control or regulate the expression of one or multiple…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: induced pluripotent stem cells are the type of stem cells that are produced from the somatic cells…

Q: Discuss the relationship between cancer and changes in gene expression that affect cell…

A: Cancer is the condition in which the control over the process of cell division is lost.