Please answer question 8 If a particular proto-oncogene has been altered by mutation into anoncogene such that it is contributing to a cancer phenotype, which ofthe following must be TRUE?One copythegene must have gain-of-function mutations in any cellBoth copies the gene must have loss-of-function mutations in the same cellMore than one of the listed options is possibleOneсорythegene must have loss-of-function mutations in a cellBoth copies the gene must be hypermethylated in the same cell

Proto oncogenes are the genes which are inactivated in normal cell but when they get activated, it…

Answered: If a particular proto-oncogene has been…

If a particular proto-oncogene has been altered by mutation into an oncogene such that it is contributing to a cancer phenotype, which of the following must be TRUE?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter12: Genes And Cancer

Section: Chapter Questions

Problem 15QP: Which of the following mutations will result in cancer? a. homozygous recessive mutation in a...

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Question

Please answer question 8

If a particular proto-oncogene has been altered by mutation into an
oncogene such that it is contributing to a cancer phenotype, which of
the following must be TRUE?
One copy
the
gene must have gain-of-function mutations in any cell
Both copies the gene must have loss-of-function mutations in the same cell
More than one of the listed options is possible
One
сорy
the
gene must have loss-of-function mutations in a cell
Both copies the gene must be hypermethylated in the same cell

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