Identify (draw) the stable intermediate and explain why it is stable.

Pushing Electrons
4th Edition
ISBN:9781133951889
Author:Weeks, Daniel P.
Publisher:Weeks, Daniel P.
Chapter5: Some Reactions From Biochemistry
Section: Chapter Questions
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Neostigmine is an inhibitor of acetylcholinesterase. The enzyme attempts to catalyse the same reaction on neostigmine as it does with acetylcholine. However, a stable intermediate is formed which prevents completion of the process and which results in a molecule being covalently linked to the active site. Identify (draw) the stable intermediate and explain why it is stable.
Neostigmine is an inhibitor of acetylcholinesterase. The enzyme attempts to
catalyse the same reaction on neostigmine as it does with acetylcholine.
However, a stable intermediate is formed which prevents completion of the
process and which results in a molecule being covalently linked to the active
site. Identify (draw) the stable intermediate and explain why it is stable.
N-
Neostigmine
Transcribed Image Text:Neostigmine is an inhibitor of acetylcholinesterase. The enzyme attempts to catalyse the same reaction on neostigmine as it does with acetylcholine. However, a stable intermediate is formed which prevents completion of the process and which results in a molecule being covalently linked to the active site. Identify (draw) the stable intermediate and explain why it is stable. N- Neostigmine
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