In expressing therapeutic proteins (check all that apply):O Bacteria could be used if you want the protein's disulfide bonds formed before secretion from the bacterial cell.The N-terminal signal sequence and the C chain of insulin must be cleaved off in the rough ER before it's active.O Proteolytic protein maturation can be performed by mammalian cells.□ One of the required modifications to preproinsulin, before it's mature, is glycosylation.Both preproinsulin and proinsulin are inactive proteins.

Therapeutic proteins are genetically engineered proteins of mammalian origin. These proteins are…

Answered: In expressing therapeutic proteins…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter32: The Reception And Transmission Of Extracellular Information

Section: Chapter Questions

Problem 5P

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