Intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Na+-glucose symporter. Recall that the Na+ concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" transport of two Na+ ions into the cell to the "uphill" transport of glucose into the cell. If the Na* concentration outside the cell ([Na*lout) is 149 mM and that inside the cell ([Na*]in) is 21.0 mM, and the cell potential is –54.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C. kJ What is the maximum ratio of [glucose];n [glucose]out AGgluc = mol that could theoretically be produced if the energy coupling were 100% efficient? 3.5 x 10–4 7.96 2900 1.13 O O O

Chemistry: The Molecular Science
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Chapter10: Fuels, Organic Chemicals, And Polymers
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Intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Na+-glucose symporter.
Recall that the Na+ concentration is significantly higher outside the cell than inside the cell. The symporter couples the
"downhill" transport of two Na+ ions into the cell to the "uphill" transport of glucose into the cell.
If the Na* concentration outside the cell ([Na*lout) is 149 mM and that inside the cell ([Na*]in) is 21.0 mM, and the cell
potential is –54.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the
cell. Assume the temperature is 37 °C.
kJ
What is the maximum ratio of [glucose];n
[glucose]out
AGgluc =
mol
that could theoretically be produced if the energy coupling
were 100% efficient?
3.5 x 10–4
7.96
2900
1.13
O O O
Transcribed Image Text:Intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Na+-glucose symporter. Recall that the Na+ concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" transport of two Na+ ions into the cell to the "uphill" transport of glucose into the cell. If the Na* concentration outside the cell ([Na*lout) is 149 mM and that inside the cell ([Na*]in) is 21.0 mM, and the cell potential is –54.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C. kJ What is the maximum ratio of [glucose];n [glucose]out AGgluc = mol that could theoretically be produced if the energy coupling were 100% efficient? 3.5 x 10–4 7.96 2900 1.13 O O O
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