Let's say an autosomal gene undergoes mutation in a population of 28 barn cats to become a new neutral allele. Calculations are required to answer these questions with numbers (Random/spam answers will be reported to chegg) 1. What would be the probability that the allele becomes fixed? 2. What is the probability that it becomes lost overtime? 3. What would the average time to fixation be, assuming that it is eventually fixed?

Let's say an autosomal gene undergoes mutation in a population of 28 barn cats to become a new neutral allele. Calculations are required to answer these questions with numbers (Random/spam answers will be reported to chegg) 1. What would be the probability that the allele becomes fixed? 2. What is the probability that it becomes lost overtime? 3. What would the average time to fixation be, assuming that it is eventually fixed?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter5: The Inheritance Of Complex Traits

Section: Chapter Questions

Problem 5QP: As it turned out, one of the tallest Potsdam Guards had an unquenchable attraction to short women....

See similar textbooks

Similar questions

a. Alleles of genes on the X chromosome can also be atequilibrium, but the equilibrium frequencies underthe Hardy-Weinberg assumptions must be calculatedseparately for the two sexes. For a gene with two alleles A and a at frequencies of p and q, respectively,write expressions that describe the equilibrium frequencies for all the genotypes in men and women.b. Approximately 1 in 10,000 males in the UnitedStates is afflicted with hemophilia, an X-linkedrecessive condition. If you assume that the population is at Hardy-Weinberg equilibrium, what proportion of American females would be hemophiliacs?About how many female hemophiliacs would youexpect to find among the 170 million women livingin the United States? (Assume that all females withhemophilia are homozygous for the disease allele.)
Consider the case of a hypothetical genetic disease called WhySciEleven (WSE), an inherited disease that results to the inability to complete production of an amino acid “moduleactivity” that results in brain damage if untreated. WSE is due to a recessive allele. Given one WSE occurrence per 10,000 births. Which term in the Hardy-Weinberg equation corresponds to the frequency of individuals who have no alleles for the disease WSE? a. p b. 2pq c. p2 d. q2
Duchenne muscular dystrophy is sex linked and usuallyaffects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brotherhas Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’sdisease, what is the probability that you have receivedthe allele?c. If your father’s brother had the disease, what is theprobability that you have received the allele?
The distance between two molecular markers that are linked alongthe same chromosome can be determined by analyzing the outcomesof crosses. This can be done in humans by analyzing a family’spedigree. However, the accuracy of linkage mappingwith human pedigrees is fairly limited because the number of people in mostfamilies is relatively small. As an alternative, researchers can analyze a population of sperm, produced from a single male, and computelinkage distance in this manner. As an example, let’s suppose a maleis heterozygous for two polymorphic STSs. STS-1 exists in two sizes:234 bp and 198 bp. STS-2 also exists in two sizes: 423 bp and 322bp. A sample of sperm was collected from this man, and individualsperm were placed into 40 separate tubes. In other words, there wasone sperm in each tube. Believe it or not, PCR is sensitive enough toallow analysis of DNA in a single sperm! Into each of the 40 tubeswere added the primers that amplify STS-1 and STS-2, and then thesamples were…
In a large, randomly mating population, the frequency of the allele (s)for sickle-cell hemoglobin is 0.028. The results of studies have shownthat people with the following genotypes at the beta-chain locus producethe following average numbers of offspring:Genotype Average numberof offspring producedSS 5Ss 6ss 0a. What will the frequency of the sickle-cell allele (s) be in the nextgeneration?b. What will the frequency of the sickle-cell allele be at equilibrium?
In the Human Genome Project, researchers have collectedlinkage data from many crosses in which the male washeterozygous for molecular markers and many crosses wherethe female was heterozygous for the markers. The distancebetween the same two markers, computed in map units, isdifferent between males and females. In other words, thelinkage maps for human males and females are not the same.Propose an explanation for this discrepancy. Do you think thesizes of chromosomes (excluding the Y chromosome) in humanmales and females are different? How could physical mappingresolve this discrepancy?
Tay-Sachs disease is caused by loss-of-function mutations in a gene on chromosome 15 thatencodes a lysosomal enzyme. Tach-Sachs is inherited as a autosomal recessive conidition.Among Ashkenazi Jews of central European ancestry, about 1 in 3600 children is born withthe disease. What fraction of the individuals in this population are carriers? (Assume thepopulation is in Hardy-Weinberg equilibrium)
The equation p2+ 2pq + q2= 1 representing theHardy-Weinberg proportions examines genes withonly two alleles in a population.a. Derive a similar equation describing the equilibrium proportions of genotypes for a gene withthree alleles. [Hint: Remember that the HardyWeinberg equation can be written as the binomialexpansion (p + q)2.]b. A single gene with three alleles (IA, IB, and i) isresponsible for the ABO blood groups. Individualswith blood type A can be either IA IAor IA i;those with blood type B can be either IB IBor IB i;people with AB blood are IA IB, and type O individuals are ii. Among Armenians, the frequency of IAis0.360, the frequency of IBis 0.104, and the frequencyof i is 0.536. Calculate the frequencies of individuals in this population with the four possible bloodtypes, assuming Hardy-Weinberg equilibrium.In Problems 15–17, you will see that because matingbetween individuals within populations at Hardy-Weinbergequilibrium is random, it is possible to predict…
Suppose you want to develop a population of Drosophila thatwould rapidly learn to avoid certain substances the flies coulddetect by smell. Based on the heritability estimate you obtainedin Problem 17, do you think it would be worth doing this by artificialselection? Why or why not?
. For several years, Hans Nachtsheim investigated an inherited anomaly of the white blood cells of rabbits. Thisanomaly, termed the Pelger anomaly, is the arrest ofthe segmentation of the nuclei of certain white cells. Thisanomaly does not appear to seriously burden the rabbits.a. When rabbits showing the Pelger anomaly were matedwith rabbits from a true-breeding normal stock,Nachtsheim counted 217 offspring showing the Pelgeranomaly and 237 normal progeny. What is the geneticbasis of the Pelger anomaly?b. When rabbits with the Pelger anomaly were matedwith each other, Nachtsheim found 223 normal progeny,439 with the Pelger anomaly, and 39 extremely abnormalprogeny. These very abnormal progeny not only haddefective white blood cells, but also showed severedeformities of the skeletal system; almost all of themdied soon after birth. In genetic terms, what do yousuppose these extremely defective rabbits represented?Why were there only 39 of them?c. What additional experimental evidence…
. In 1919, Calvin Bridges began studying an X-linkedrecessive mutation causing eosin-colored eyes inDrosophila. Within an otherwise true-breedingculture of eosin-eyed flies, he noticed rare variantsthat had much lighter cream-colored eyes. By intercrossing these variants, he was able to make a truebreeding cream-eyed stock. Bridges now crossedmales from this cream-eyed stock with true-breedingwild-type females. All the F1 progeny had red (wildtype) eyes. When F1 flies were intercrossed, the F2progeny were 104 females with red eyes, 52 maleswith red eyes, 44 males with eosin eyes, and14 males with cream eyes. Assume that thesenumbers represent an 8:4:3:1 ratio.a. Formulate a hypothesis to explain the F1 and F2results, assigning phenotypes to all possiblegenotypes.b. What do you predict in the F1 and F2 generations if the parental cross is between truebreeding eosin-eyed males and true-breedingcream-eyed females?c. What do you predict in the F1 and F2 generationsif the parental cross is…
Let’s suppose that weight in a species of mammal is polygenic, andeach gene exists as a heavy and light allele. If the allele frequenciesin the population are equal for both types of alleles (i.e., 50%heavy alleles and 50% light alleles), what percentage of individualswill be homozygous for the light alleles in all of the genesaffecting this trait, if the trait was determined by the followingnumber of genes?A. TwoB. ThreeC. Four