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- - Multiple Choice - Explain your answer in 3-5 sentences. - answer properly QUESTION: Removal of phosphoryl groups is catalyzed by ___________ a. Diphteria toxin and cholera toxin b. Dinitrogenase reductase c. Protein phosphatases d. Protein kinasesCHOOSE THE BEST ANSWER: 2. ALL are true about the activity of Macrolides EXCEPT: It is effective against syphilis infections it resembles that of penicillin it is very effective against G(-) bacteria it is effective against erysipelas infections 3. These are ALL causes of bacterial resistance against macrolides EXCEPT: active efflux bacterial endospores release of esterases modification of binding site 4. These are ALL adverse effects of Erythromycin EXCEPT: CYP450 inhibition Hepatotoxicity Neutropenia Acute cholestatic hepatitis 5. These are drugs that have prolonged half-life when taken with erythromycin EXCEPT: Rifampicin Lipitor Lanoxin LasixPlease answer fast 9. Traditional coagulase testing involves the detection of coagulase (slide test) or detection of both bound and free coagulase (tube test). Describe newer methods of Staphylococcus aureus identification such as latex coagglutination tests. What specific cell components are detected? 10. Name two media used to isolate Staphylococcus from mixed flora specimens and one for use with pure cultures
- Answer the following questions in complete sentences and paragraphs. Draw the diagram by hand: Diagram the 5 step pathogenesis cycle for coli O157:H7, an extracellular, intestinal pathogen acquired by consuming contaminated food/water. Be sure to include the role of exoenzymes and the Shiga exotoxin in your diagram. Explain the pathogenesis of Listeria monocytogenes. Be sure to include temperature regulation, intracellular growth, and at risk groups in your discussion.Hello! -how can xenobiotics access the host through the diet, air, drinking water and drug administration? -what harms do xenobiotics cause? ( toxicokinetically and toxicodynamically). Thank you very much!Please answer fast 1.Distinguish between drug toxicity and allergic reactions to drugs. 2. List five cellular or structural mechanisms that microbes use to resist antimicrobials. .
- Why is bile acid binding resins not used for hypertrigliceridemia (high TG)? Please shortly answer at your own words.Thanking you in advance for your help List the cell wall components that contribute to virulence by protecting the bacteria from immune responses. List those that contribute to virulence by eliciting toxic responses in the human hostWrite about Oxford–AstraZeneca COVID-19 vaccine (Covishield) You must include the following information Chemistry of the drugs: Structure, physicochemical properties, (log P, pKa, & stereochemistry) and chemical properties and stability. Mechanism of action: (including the possible drug target interactions) in CoVid-19 Pharmacokinetic: Absorption, distribution (% plasma binding), chemical basis of metabolic pathways and elimination Pharmacological properties including side effect, ADR, drug interaction, precautions, dose and dosage forms Stability and storage conditions, as well as Brand names
- Answer the following: 1.) In the Philippines, treatment for paralytic shellfish poisoning includes ________ which has a detoxification action 2.) a toxin found in contaminated shellfish 3.) a drug that will help manage the seizure episode of an individual who is intoxicated with TCA's 4.) Why emetics not recommended in salicylate poisoning? 5.) A hereditary disease cause by an abnormal absorption of iron in the gut lumen 6.) the toxic part of of tuba tuba plant 7.) the ultrashort acting barbiturate 8.)An antidote for benzodiazepine poisoning/overdosage27. Why should ciprofloxacin use be limited in pregnant women and children? Group of answer choices it causes softness of teeth it is associated with vasodilation and anaphylactic shock it affects cartilage development it disrupts normal flora; induces pseudomembranous colitis it induces aplastic anemia it's toxic to kidneys 28. Vancomycin, a narrow spectrum antibiotic that targets bacterial cell wall. What's the mechanism of action ? Group of answer choices prevents cross bridging ; binds to amino acid of the tetrapeptide chain breaks down beta lactam ring inhibits precursors transport across the membrane binds to PBP and prevents cross bridging interferes with ala-ala bridge in Gram (+)ve bacteria inhibits mycolic acid synthesisReviewing drug characteristics, choose an antimicrobial for each ofthe following situations (explain your choice):a. for an adult patient suffering from Mycoplasma pneumoniab. for a child with bacterial meningitis (drug must enter intocerebrospinal fluid) c. for a patient who has chlamydiosis and an allergy to azithromycind. for PPNG drug-resistant gonorrhea
