Since in this patient pyruvate kinase is abnormal not only is less pyruvate made but intermediates above pyruvate in the glycolytic pathway build up slowing the pathway. which of the following would be expected? A.ADP to ATP ratios would be elevated above normal. B.NADP+ would increase relative to NADPH. C.Ribulose 5-phosphate levels would decrease. D.NADH to NAD+ ratios would decrease. E.Methemoglobin levels would increase.

Since in this patient pyruvate kinase is abnormal not only is less pyruvate made but intermediates above pyruvate in the glycolytic pathway build up slowing the pathway. which of the following would be expected? A.ADP to ATP ratios would be elevated above normal. B.NADP+ would increase relative to NADPH. C.Ribulose 5-phosphate levels would decrease. D.NADH to NAD+ ratios would decrease. E.Methemoglobin levels would increase.

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter4: How Cells Obtain Energy

Section: Chapter Questions

Problem 9RQ: What do the electrons added to NAD do? a. They become part of a fermentation pathway. b. They go to...

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If the enzyme that catalyzed the reaction that converts pyruvate to acetyl-CoA and carbon dioxide is inhibited: a. the production of ATP would decreases but the production of electron carriers would be unaffected b. the concentration of pyruvate would decrease c. the citric acid cycle will not be affected d. ATP production in the electron transport chain/oxidative phosphorylation will increase e. the concentration of acetyl Co A would decrease
Which of the following stimulates the conversion of pyruvate to acetyl-CoA? a) Activation of pyruvate dehydrogenase kinase b) A decrease in the ratio of NAD+/NADH c) Bothaandb d) Neither a nor b
a) Using full chemical structures of substrates and products, draw the two possible pyruvate reduction pathways that regenerate NAD+ from NADH in the absence of oxygen gas. Give names of all compounds and enzymes involved. b) Draw the step in glycolysis that requires at least one of the above pathways to be functional in the absence of oxygen. Give names of all compounds and enzymes involved.
Oxidative decarboxylation a. Do not occur in the TCA cycle. b. Involve loss of CO2 and the production of NADH. c. Involve loss of CO2 and the production of NAD. d. Involve loss of CO2 and the production of FADH2.
Which of the given process does not occur in mitochondria? a.Formation of acetyl CoA b.Oxidation of NADH + Ht c.Citric acid formation d.Conversion of pyruvic acid to acetaldehyde
What effect will increasing the number of c subunits in ATP synthase have on the P:O ratio? A. It will increase for both NADH and FADH2. B. It will increase for NADH and decrease for FADH2. C. It will decrease for NADH and increase for FADH2. D. It will decrease for both NADH and FADH2. E. It will remain unchanged for both NADH and FADH2.
The consumption of acetyl-CoA by the citric acid cycle is DECREASED under which condition? A. the concentration of NAD+ being high B. the concentration of oxaloacetate being high C. NADH being rapidly re-oxidized via the electron-transport chain D. the mitochondrial ATP synthase being inactive E. the concentration of both NAD+ and oxaloacetate being high
Why is there a difference in the ATP that is being produced by the NADH molecule coming from Glycolysis which could be 4-6 for 2 NADH molecules? a.The conversion of reduction of NAD+ to NADH is a highly energetic process. b.Glycolysis uses 2 ATP for the production of NADH. c.NADH molecules from Glycolysis is not energetic enough to produce the 3 ATP. d.It will be dependent on the pathway that the NADH will be undergoing.
During cellular respiration, 60 molecules of CO2 were given off as waste. a. How many pyruvate molecules were produced in glycolysis? b. The total amount of ATP produced by complete cellular respiration would be? c. The amount of energy available (Net ATP) to cell as ATP would be?
Which of these is associated with production of ATP during glycolysis? (Select all that apply) a) Conversion of 1,3-BPG to 3PG b) Conversion of 1,3-BPG to 2,3-BPG c) Conversion of PEP to pyruvate d) Conversion of 2,3-BPG to 2PG e) Phosphorylation of glucose
A key enzyme of the Citric Acid Cycle is isocitrate dehydrogenase. It catalyzes the conversion of isocitrate to alpha ketoglutarate. Given your understanding of the Citric Acid Cycle, how is the activity of isocitrate dehydrogenase likely regulated? A. It is activated when fermentation starts. B. It is activated when the levels of NADH are low relative to NAD+. C. It is activated when levels of ATP are high relative to ADP. D. It is inhibited by high levels of pyruvate.
When rotenone is added to actively respiring bovine mitochondria, the ratio of NADH to NAD+ increases but the FADH2 to FAD ratio remains unchanged. a. What step in the system is being inhibited by rotenone? b. What would be the effect of rotenone on pyruvate oxidation to CO2? ____________________ Why?