Suppose your TLC plate looks like the image below (ran 1:1 ratio ethyl acetate/hexane). What is the Rf value of the red compound (lower compound, 1 cm from the baseline)? How could the solvent combination be varied to lower the Rf value of the red product? How can we change the eluent composition to improve the separation of the two products on column chromatography? Solvent line 6.8 cm 5.1 cm X--X-- Base line SM Co P rf value choices: 0.1, 0.15, 0.25, 0.3, 0.35, 1.15 how could solvent combination be varied choices: increase ratio of hexane or decrease ratio of hexane how can we change eluent composition choices: start with more polar eluent or start with less polar eluent

Suppose your TLC plate looks like the image below (ran 1:1 ratio ethyl acetate/hexane). What is the Rf value of the red compound (lower compound, 1 cm from the baseline)? How could the solvent combination be varied to lower the Rf value of the red product? How can we change the eluent composition to improve the separation of the two products on column chromatography? Solvent line 6.8 cm 5.1 cm X--X-- Base line SM Co P rf value choices: 0.1, 0.15, 0.25, 0.3, 0.35, 1.15 how could solvent combination be varied choices: increase ratio of hexane or decrease ratio of hexane how can we change eluent composition choices: start with more polar eluent or start with less polar eluent

Principles of Instrumental Analysis

7th Edition

ISBN:9781305577213

Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Chapter28: High-performance Liquid Chromatography

Section: Chapter Questions

Problem 28.19QAP

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