what is pharmacophore? what is the importance of pharmacophore in drug discovery?

Q: What is pharmacophore? write about its significance in drug discovery? briefly explain

A: The drug is the chemical substance that is responsible for altering the function of living things.…

Q: What is the ultimate goal of drug metabolism? Discuss with example.

A: Drugs are any substances when taken into the body bring out psychological and physiological changes…

Q: Please design a hypothetical targeted drug delivery system and explain it in detail

A: Drug targeting refers to the delivery of medications to specific receptors, organs, or other bodily…

Q: What is the present status of drug discovery research for COVID-19? Find articles/ researches that…

A: COVID-19:- Coronaviruses are a type of virus that can infect humans and cause respiratory disease.…

Q: Explain the effect of COM-blockers on bacterial transformation and their application in controlling…

A: Pathogens are disease-causing organisms that can cause humans to become ill or die depending on the…

Q: What is a pharmacopeial monograph? Based on the USP XXII and NF XVIII, list the part of a monograph…

A: A pharmacopeia is a document made by the authorities of the nation to standardize the production of…

Q: Explain the role of LC50 in ensuring the safety of a drug candidate? Explain at your own words

A: Drugs are defined as the type of chemical substances where they produce changes in the physiology or…

Q: Define therapeutic index and explain its importance.

A: Therapeutic Index is also known as Therapeutic Ratio. It is a quantitative measurement of the…

Q: Describe the different types of trials a new drug must undergo before it is “ready for market.”

A: A drug is a chemical substance that produces a biological effect. When the drug is taken by…

Q: What is the purpose of a closure( pharmaceutical) ?  What are the characteristics of a good closure?

A: In the packaging of sterile products, closures that are part of the container-closure system play a…

Q: Why is it better for a drug to be microbicidal than microbistatic?

A: Any substance which is produced by naturally, artificially or through synthetic origin that kills or…

Q: In what cellular process does the drug target play a role?

A: Cells are separated from their surroundings by the cell membrane.

Q: How does physicochemical properties of a drug define its biological mechanism? Please explain at…

A: A drug is considered a substance that tends to cause certain changes in physiological functions. The…

Q: ase give point on

A: Drugs are any substances when taken into the body bring out psychological and physiological changes…

Q: What happens in phase 1 drug metabolism?

A: Drug metabolism is the process in which drug undergoes some chemical changes and gets biotransformed…

Q: . Relationship of Drug solubility & dissolution rate on Physico-Chemical Properties 2.…

A: 1.Physicochemical properties: The ability of a chemical compound to elicit a pharmacological/…

Q: what are the facilitated transport system for drug absorption?

A: Drug absorption refers to the phenomenon of the drug molecules to enter into the blood circulation…

Q: what are the pharmacodynamics factors that we can improve for the H1-Antihistamine drug development?

A: The study involving the biochemical reactions and effect of the drug on the body is called…

Q: What is DEA number ? why we use this number in the prescription? what is the importance of DEA…

A: Controlled substances are drugs that are associated with a high risk of abuse, addiction and…

Q: explain what scaffold hopping is and why it is useful for drug development?

A: According to the question we have to explain scaffold hopping. In addition to that, we need to…

Q: What are some of the challenges in the use of ASOs as therapeutics? How are scientists addressing…

A: The concept of an Antisense oligonucleotide (an ASO) was first introduced by Stephenson and…

Q: Describe the influence of protein binding on drug bioavailability

A: Protein binding is the extent to which drugs can bind to proteins in the blood or tissues. The…

Q: The key element that would transform a matrix-type extended-release drug product to a reservoir-type…

A: Answer--  water insoluble rate cintrolling Membrane

Q: What is meant by drug discovery. Describe the process by elaborating steps involved in drug…

A: Humans are organisms that require protection against several other organisms. The immune system is…

Q: Please What Is the main difference between Medicines and Drugs?

A: A disease is diagnosed based on certain symptoms and laboratory tests. Some diseases require…

Q: What do you know about pharmacodynamic and pharmacokinetic drug development?

A: Drug development begins in the laboratory with lab. and animal testing to ensure complete safety.…

Q: How do uncoupling agents work?

A: Uncoupling agents are also known as uncoupler. They are molecules that disrupts the oxidative…

Q: How we can improve (potency, selectivity and decrease in toxicity ) for the development of a…

A: Antihistamines are drugs that are used to treat allergic conditions like sneezing, runny nose,…

Q: Below, you can see a picture of an antimicrobial drug. Regarding semi-synthetic antimicrobial drug…

A: Antibiotic resistance happens when germs develop the ability to defeat the drugs that are designed…

Q: At what stage of the drug development pathways can molecular conjugation and bioconjugation based…

A: Conjugation-  Glucuronidation, the most common phase II reaction, is the only one that occurs in the…

Q: Write the Drug Discovery Process of Diltiazem?

A: *The revelation of Ca++ antagonism as a modern principle of activity of coronary drugs comes back to…

Q: Explain the drug discovery process of Losartan?

A: Drug discovery process of Losartan Saralasin is an octa-peptide counterpart of Ang II that replaces…

Q: what are the purpose of drug metabolism?

A: Drug metabolism is metabolic breakdown of drugs in the body with the help of specific enzymes. It is…

Q: What are the different methods for developing modified release drug delivery system ? Discuss about…

A: Modified release means the sustained or controlled release of active ingredients of drugs taken…

Q: how does protein binding affect the drug action

A: Many drug molecules interact with the plasma protein and tissue proteins or with other important…

Q: What are Targeted drug delivery systems ? Please explain the ideal properties of Targeted drug…

A: A drug is a molecule which might resemble a organic molecule inside the body or an exogenous…

Q: What is amoxicillin brand and generic names? Discuss the actions, uses, contraindications, adverse…

A: INTRODUCTION- Antibiotics can be defined as the are medications that act against the bacterial…

Q: What is the process that leads to drug tolerance?

A: The effect of the drug lessens with repeated exposure. Bigger doses drug is required to bring…

Q: Describe the role of receptor sites in drug action.

A: Receptors are the macromolecule which are present in the membrane or in the cell wall, that…

Q: Please write the Drug Discovery process  of Losartan?  Please write at your own words.

A: Losartan is a antihypertensive drug which was the first angiotensin II receptor antagonist. The…

Q: Please give me a discussion/explanation of (CLINICAL TRIAL) part in drug discovery and development.

A: The pharmaceutical sector is a very significant field nowadays since the discovery of new…

Q: Briefly discuss how we can improve pharmacodynamic properties of H1-Antihistamine drugs?

A: The study involving the biochemical reactions and effect of the drug on the body is called…

Q: Define the concept of drug bioavailability and briefly explain how it is experimentally determined.…

A: bio-availability of a drug is the indicator or measure to check how much the administered dosage of…

Q: What do you know about pharmacodynamic and pharmacokinetic drug development? Explain briefly

A: Drug research:It encompasses many diverse disciplines that are united for a common goal, the…

Q: What are the three main targets of drug design and development?

A: Any non-food substances that bring out changes in psychology and physiology when taken in are called…