What is unique about how acetyl-CoA carboxylase 1 is regulated compared to any enzyme in glycolysis? Some phospholipid species can be phosphorylated beyond the phosphate attached to the #3 carbon. Describe the likely structure of such a phospholipid. Would the mass / charge (m/z) ratio of this molecular increase or decrease upon modification? Mechanistically, how does NADPH facilitate the removal of an oxygen atom from intermediates in fatty acid synthesis? Will a phosphatidylcholine or a phosphatidylethanolamine have a larger mass / charge (m/z) ratio?

What is unique about how acetyl-CoA carboxylase 1 is regulated compared to any enzyme in glycolysis? Some phospholipid species can be phosphorylated beyond the phosphate attached to the #3 carbon. Describe the likely structure of such a phospholipid. Would the mass / charge (m/z) ratio of this molecular increase or decrease upon modification? Mechanistically, how does NADPH facilitate the removal of an oxygen atom from intermediates in fatty acid synthesis? Will a phosphatidylcholine or a phosphatidylethanolamine have a larger mass / charge (m/z) ratio?

Name: What is unique about how acetyl-CoA carboxylase 1 is regulated compare
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: What is unique about how acetyl-CoA carboxylase 1 is regulated compared to any enzyme in glycolysis?Some phospholipid species can be phosphorylated beyond the phosphate attached to the #3 carbon. Describe the likely structure of such a phospholipid.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 21P: Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and...

See similar textbooks

Similar questions

Using the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved residues in slightly different positions can change the catalytic rate of reaction.
Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.
Both prokaryotic and eukaryotic organisms carry out some form of glycolysis. How does ha fact support or not support the assertion that glycolysis is one of the oldest metabolic pathways?
If oxidation of acetyl-CoA yields 10 ATPs per mole through the citric acidcycle, how many ATPs will be derived from the complete metabolic oxidation of 1 mole of alanine in a mammal? Would the corresponding energyyield in a fish be higher or lower? Why? How much energy would bederived from the metabolic oxidation of 1 mole of isoleucine to CO2, H2O,and NH3? Of tyrosine?
Acetly CoA can quickly enter the citric acid cyle by joining with a C4 compound and forming citrate. Meanwhile, GTP (or ATP) is generated using inorganic phosphate while succinyl CoA is converted to succinate. What is the main reason both acetly CoA and succinyl CoA can perform such work? a. Acetyl CoA and succinyl CoA both contain coenzyme A, which is a high-energy compound. b. Acetyl CoA and succinyl CoA both form an unstable thioester bond with coenzyme A. c. Acetyl CoA and succinyl CoA both bind with inorganic phosphate which is used to generate ATP (or GTP). d. Acetyl CoA and succinyl CoA both transiently form a covalent bond with the enzymes that catalyze the next reaction, pyruvate dehydrogenase and succinyl-CoA synthetase, respectively. e. Acetyl CoA and succinyl CoA use the energy collected from the electron transport chain.
Anabolic reactions like fatty acid synthesis are inherently endergonic and require exergonic driving forces to proceed forward. Which of the following statements correctly describes the thermodynamics at play in the substrate activation step of fatty acid synthesis and the importance of this step in downstream elongation of the fatty acid chain? (A) Acetyl CoA carboxylase (ACC1) provides free energy that powers the carboxylation of acetyl CoA to form malonyl CoA.(B) The formation of malonyl CoA is powered by the exergonic carboxylation of acetyl CoA.(C) The formation of a b-ketoacyl ACP in the first step of fatty acid synthesis is driven forward because b-ketoacyl synthase hydrolyzes ATP. (D) The addition of two carbons to the growing fatty acid chain is powered by malonyl ACP decarboxylation.(E) Decarboxylation of malonyl ACP is exergonic and the free energy that is released is coupled to ATP synthesis.
If oxidation of acetyl-CoA yields 10 ATPs per mole through the citric acid cycle, how many ATPs will be derived from the complete metabolic oxidation of 1 mole of alanine in a mammal? Would the corresponding energy yield in a fish be higher or lower? Why? How much energy would be derived from the metabolic oxidation of 1 mole of isoleucine to CO2, H2O, and NH3? Of tyrosine?
Fourteen NADPH molecules are required to produce one molecules of palmitic acid from acetyl CoA. Substantiate this statement by referring to the enzymatic activities involved in reduction steps during fatty acid synthesis and the number of cycles required to produce palmitic acid from acetyl CoA. How many molecules of ATP is required for the synthesis of palmitic acid from cytosolic acetyl-CoA?
What if the phosphate group for the glycolysis reaction with enzyme glyceraldehyde 3-phosphate dehydrogenase was from ATP instead of Pi? What would the complete, balanced, net rxn of glycoslysisequation be and how does this impact the overall glycolysis rxn?
Why is the isomerization of glucose-6-phosphate (G6P) to fructose-6-phosphate (F6P) an important step in glycolysis? How is the isomerization of F6P back into G6P prevented?
Why is it advantageous for citrate, the product of Reaction 1 of the citric acid cycle, to inhibit phosphofructokinase, which catalyzes the third reaction of glycolysis?
The same reactions that were seen in the process of converting pyruvate to acetyl-S-CoA, occur in step ____ of the citric acid cycle as ____________ is converted to _________________.