What would most likely occur if glucosyltransferase were removed from the ER? BiP binding to misfolded proteins would increase and the ER would fill up with misfolded proteins Incompletely folded proteins would traffic to the Golgi ATF6 would leave the ER, activate in the Golgi, and initiate transcription of stress-relieving genes PERK would become active and inactivate elF2alpha

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter30: Protein Synthesis
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What would most likely occur if glucosyltransferase were removed from the ER?
BİP binding to misfolded proteins would increase and the ER would fill up with misfolded
proteins
Incompletely folded proteins would traffic to the Golgi
ATF6 would leave the ER, activate in the Golgi, and initiate transcription of stress-relieving
genes
PERK would become active and inactivate elF2alpha
Transcribed Image Text:What would most likely occur if glucosyltransferase were removed from the ER? BİP binding to misfolded proteins would increase and the ER would fill up with misfolded proteins Incompletely folded proteins would traffic to the Golgi ATF6 would leave the ER, activate in the Golgi, and initiate transcription of stress-relieving genes PERK would become active and inactivate elF2alpha
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