Which of the following mutations would likely have the greatest negative impact on the protein product of a gene? Group of answer choices a single base deletion close to the end of the coding region of a gene a single base insertion just after the start of the coding region of the gene a deletion of three bases near the middle of the gene a base-pair substitution

Which of the following mutations would likely have the greatest negative impact on the protein product of a gene? Group of answer choices a single base deletion close to the end of the coding region of a gene a single base insertion just after the start of the coding region of the gene a deletion of three bases near the middle of the gene a base-pair substitution

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Description: Which of the following mutations would likely have the greatest negative impact on the protein product of a gene?Group of answer choicesa single base deletion close to the end of the coding region of a genea single base insertion just after the start

Biology Today and Tomorrow without Physiology (MindTap Course List)

5th Edition

ISBN:9781305117396

Author:Cecie Starr, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Christine Evers, Lisa Starr

Chapter7: Gene Expression And Control

Section: Chapter Questions

Problem 9SQ

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The promoter and terminator regions of genes are important in: a. coding for amino acids b. gene regulation c. structural support for the gene d. intron removal e. anticodon recognition
Which of the following mutations would have the greatest negative impact on the protein product of a gene? A. a single base deletion close to the end of the coding region of a gene. B. a single base insertion near the start of the coding region of the gene C. a base-pair substitution D. a deletion of three bases near the middle of the gene
The template strand of a gene contains the following sequence: 3'-TAC TTG TCC GAT ATC-5' Following a mutation, the sequence is modified for this one: 3'-TAC ATG TCC GAT ATC-5' Draw the sequence of a.a. encoded for each of the strands. What is the effect of this mutation on the sequence amino acids (specify type of mutation)
Which of the following mutations would be most likely to have the most negative effect on the functioning of a protein produced by the gene? Group of answer choices a deletion of one nucleotide at the beginning of the coding sequence a substitution of one nucleotide at the beginning of the coding sequence an insertion of three nucleotides near the end of the coding sequence a substitution of one nucleotide near the end of the coding sequence
Which of the following mutations is most likely to cause a single amino acid difference during the translation of mRNA into protein? A. Single base-pair insertion B. Single base-pair deletion C. Mutations in regulatory sites D. Base-pair substitution
A small section of a gene for a protein has the following nucleotide sequence: CTA TCC CCT ACG TCA Which of the following mutations would cause a silent mutation in the sequence shown above? a. Replacement of first thymine base with adenine base b. Replacement of second thymine base with guanine base c. Replacement of first cytosine base with guanine base d. Replacement of second adenine base with thymine base
Which type of mutation would expect would have no effect on a protein coding gene in eukaryotes? a.a single base substitution that creates a splice site mutation b.a single base substitution that creates a synonymous mutation c.a single base deletion that creates a frameshift near the 3' end of the open reading frame d.a single base substitution that creates a non-conservative missense mutation e.a single base substitution that creates a conservative missense mutation
A protein was mutated at amino acid position 129. Which of the following mutations will least effect the protein's function? a.) R mutated to K b.) R mutated to L c.) R mutated to A d.) R mutated to D
A small section of a gene for a protein has the following nucleotide sequence: TAT AGG GAC CTA TGT Which of the following mutations would cause a missense mutation in the sequence shown above? a. Replacement of first cytosine base with guanine base b. Replacement of final thymine base with guanine base c. Replacement of second guanine base with cytosine base d. Replacement of first thymine base with adenine base
Which of the following mutations would be most likely to havea harmful effect on an organism?(A) a deletion of three nucleotides near the middle of a gene(B) a single nucleotide deletion in the middle of an intron(C) a single nucleotide deletion near the end of the codingsequence(D) a single nucleotide insertion downstream of, and close to,the start of the coding sequence
A mutation has occurred to a wild type mRNA sequence: Wild Type: 5’-AUG-UUG-CAA-GCG-3’ The new mutated sequence: 5’-AUG-UUG-UAA-GCG-3’ What kind of mutation has occurred? a)Silent mutation b)Missense mutation c)Nonsense mutation d)Frameshift mutation
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