Which one of the following statements is incorrect? O Lithium diisopropylamide (LDA) is one of the most useful and common strong bases used in organic chemistry. o For a successful "crossed" condensation reaction of two carbonyl compounds that both have a-hydrogens, LDA is used to form the desired enolate ion and the other carbonyl compound is added slowly O Whereas a kinetic enolate anion is formed faster, a thermodynamic enolate anion is more stable. O HO¯ or RO¯ are good bases to form the enolate of an aldehyde or ketone in an alkylation reaction. o For a successful "crossed" condensation reaction, a carbonyl compound with a- hydrogens is added slowly to a solution of the carbonyl compound without a- hydrogens and a base.

Which one of the following statements is incorrect? O Lithium diisopropylamide (LDA) is one of the most useful and common strong bases used in organic chemistry. o For a successful "crossed" condensation reaction of two carbonyl compounds that both have a-hydrogens, LDA is used to form the desired enolate ion and the other carbonyl compound is added slowly O Whereas a kinetic enolate anion is formed faster, a thermodynamic enolate anion is more stable. O HO¯ or RO¯ are good bases to form the enolate of an aldehyde or ketone in an alkylation reaction. o For a successful "crossed" condensation reaction, a carbonyl compound with a- hydrogens is added slowly to a solution of the carbonyl compound without a- hydrogens and a base.

Pushing Electrons

4th Edition

ISBN:9781133951889

Author:Weeks, Daniel P.

Publisher:Weeks, Daniel P.

Chapter3: Mechanisms

Section: Chapter Questions

Problem 29EQ

See similar textbooks

Similar questions

The mechanism of the Fischer esterification was controversial until 1938, when IrvingRoberts and Harold Urey of Columbia University used isotopic labeling to follow thealcohol oxygen atom through the reaction. A catalytic amount of sulfuric acid was addedto a mixture of 1 mole of acetic acid and 1 mole of special methanol containing the heavy18O isotope of oxygen. After a short period, the acid was neutralized to stop the reaction,and the components of the mixture were separated.H2SO4OCH3 C O H CH3 O H CH3 C O CH3 H2OO18 + +(a) Propose a mechanism for this reaction.(b) Follow the labeled 18O atom through your mechanism, and show where it is found inthe products.(c) The 18O isotope is not radioactive. Suggest how you could experimentally determinethe amounts of 18O in the separated components of the mixture
Provide the conplete mechanism. Need both formation of diazonium ion from the nitrosonium ion and the electrophilic substitution with the diazonium chloride. Plese Give Step by Step Solution Otherwise I give you DISLIKE !!
Step 2 of the iodination of benzene shows water acting as a base and removing a proton from the sigma complex. We did notconsider the possibility of water acting as a nucleophile and attacking the carbocation, as in an electrophilic addition to an alkene.Draw the reaction that would occur if water reacted as a nucleophile and added to the carbocation. Explain why this type ofaddition is rarely observed.
At first glance, it might seem possible to prepare sulfanilamide from sulfanilic acid by the set of reactions shown here. When the reaction is conducted in this way, however, a polymeric product is produced after Step 1. What is the structure of the polymer? Why does p-acetamidobenzenesulfonyl chloride not produce a polymer?
A common method where one alkyl halide is converted to another alkyl halide is known as Finkelstein reaction. In one example of this reaction the reaction of an alkyl chloride with potassium iodide is generally carry out in acetone to maximize the amount of alkyl iodine that this formed. Why does the solvent increase the amount of alkyl iodide. Hint: potassium idioide is soluble in acetone but potassium chloride is not.
The existence of the NIH shift was established by determining the major product obtained from rearrangement of the following arene oxide, in which a hydrogen has been replaced by a deuterium. a. What would be the major product if the NIH shift occurs? b. What would be the major product if the carbocation forms phenol by losing H+ or D+, rather than by going through the NIH shift?
Two mechanisms are among those that have been postulated for decomposition of aryl diazonium salts in aqueous solution containing nucleophilic anions, A—:
Outline the mechanism showing both products formed for the reaction of ammonia (2 mole equivalent) with 1-bromobutane (1 mole equivalent).
Make the mechanism of the following reactions, remember to be detailed in the steps and write all the necessary intermediaries in each case.
An inexperienced graduate student treated dec-5-ene with borane in THF, placed the flask in a refrigerator, and left for aparty. When he returned from the party, he discovered that the refrigerator was broken and that it had gotten quite warminside. Although all the THF had evaporated from the flask, he treated the residue with basic hydrogen peroxide. Tohis surprise, he recovered a fair yield of decan-1-ol. Use a mechanism to show how this reaction might have occurred.(Hint: The addition of BH3 is reversible.)
Draw the sigma complex for the formation of the bromonium electrophile with proper resonance forms for the meta bromination of toluene and for the para bromination of toluene.
We saw that acid anhydrides react with alcohols, water, and amines. In which of these reactions can the tetrahedral intermediate eliminate the carboxylate ion even if it does not lose a proton before the elimination step? Explain