Human Anatomy & Physiology (2nd Edition)
2nd Edition
ISBN: 9780134553511
Author: Erin C. Amerman
Publisher: PEARSON
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Chapter 10, Problem 1AYKA
Summary Introduction
To review:
The following:
a. Effects of curare, a poison that blocks binding of acetylcholine to its receptor at the neuromuscular junction.
b. Useful application for this type of poison.
c. The rationale behind the lethality caused by the overdose of this poison.
Introduction:
Acetylcholine is a neurotransmitter secreted by axons of the motor neurons in the synaptic cleft. This neurotransmitter is a ligand for the ligand-gated ion channels of the motor end plate. Its function is to create an action potential in the muscle after motor neuron receives stimuli. So, it is necessary for muscle contraction.
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Chapter 10 Solutions
Human Anatomy & Physiology (2nd Edition)
Ch. 10.1 - What are the two types of striated muscle?Ch. 10.1 - Which two types of muscle are involuntary?Ch. 10.1 - What is the basic function of all types of muscle...Ch. 10.1 - 4. What five properties are common to all muscle...Ch. 10.1 - Prob. 5QCCh. 10.2 - Prob. 1QCCh. 10.2 - How are the terminal cisternae related to the...Ch. 10.2 - Prob. 3QCCh. 10.2 - How does the arrangement of myofilaments produce...Ch. 10.2 - 5. Describe the structure of a sarcomere. What is...
Ch. 10.2 - Prob. 6QCCh. 10.2 - Describe the structures of thin filaments, thick...Ch. 10.2 - Prob. 8QCCh. 10.3 - What is the resting membrane potential?Ch. 10.3 - Prob. 2QCCh. 10.3 - 3. How do the electrochemical gradients for...Ch. 10.3 - What two factors generate the resting membrane...Ch. 10.3 - What is an action potential?Ch. 10.3 - What happens during the two phases of an action...Ch. 10.4 - Prob. 1QCCh. 10.4 - Prob. 2QCCh. 10.4 - 3. How does excitation from a neuron trigger...Ch. 10.4 - How are excitation and contraction coupled?Ch. 10.4 - What are the steps of the crossbridge cycle?Ch. 10.4 - Prob. 6QCCh. 10.5 - What are the two immediate energy sources for...Ch. 10.5 - How long can these immediate energy sources fuel...Ch. 10.5 - Prob. 3QCCh. 10.5 - Prob. 4QCCh. 10.5 - Prob. 5QCCh. 10.5 - Prob. 6QCCh. 10.5 - Prob. 7QCCh. 10.6 - What is a twitch contraction?Ch. 10.6 - What are the phases of a twitch contraction?Ch. 10.6 - How does the timing of a stimulus impact the...Ch. 10.6 - 4. How do fused and unfused tetanus differ?
Ch. 10.6 - 5. At what length will a sarcomere be able to...Ch. 10.6 - How do type I and type II muscle fibers differ?Ch. 10.7 - Prob. 1QCCh. 10.7 - 2. Explain the process of recruitment.
Ch. 10.7 - Prob. 3QCCh. 10.7 - 4. How do isotonic concentric, isotonic...Ch. 10.8 - Prob. 1QCCh. 10.8 - Prob. 2QCCh. 10.8 - Prob. 3QCCh. 10.8 - What conditions does excess postexercise oxygen...Ch. 10 - Mark the following statements as true or false. If...Ch. 10 - How does a skeletal muscle fiber differ...Ch. 10 - Thick filaments are composed of the protein a....Ch. 10 - Prob. 4CYRCh. 10 - Prob. 5CYRCh. 10 - Mark the following statements as true or false. If...Ch. 10 - Prob. 7CYRCh. 10 - 8. Order the following events of excitation and...Ch. 10 - 9. Which of the following statements accurately...Ch. 10 - 10. A muscle fiber relaxes when:
a. the...Ch. 10 - Which of the following energy sources would...Ch. 10 - 12. Mark the following statements as true or...Ch. 10 - Prob. 13CYRCh. 10 - 14. Muscle tone is:
a. the result of voluntary...Ch. 10 - Prob. 15CYRCh. 10 - Which of the following is not likely to result...Ch. 10 - Which of the following factors is/are responsible...Ch. 10 - 18. What is thought to cause excess postexercise...Ch. 10 - Prob. 19CYRCh. 10 - 20. Which of the following best describes...Ch. 10 - Mark the following statements as true for smooth...Ch. 10 - Prob. 1CYUCh. 10 - Prob. 2CYUCh. 10 - 3. The drug neostigmine blocks the activity of...Ch. 10 - Explain why cardiac muscle cells and some smooth...Ch. 10 - Prob. 1AYKACh. 10 - Prob. 2AYKACh. 10 - Prob. 3AYKACh. 10 - Prob. 4AYKACh. 10 - Prob. 5AYKBCh. 10 - Prob. 6AYKB
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- If a patient was bitten by a poisonous spider (black widow) and the effects of its venom occurred at the neuromuscular junction in the peripheral nervous system, what neurotransmitter would be affected by this venom? And explain the mechanism of action of how the venom is a direct antagonist to this neurotransmitter.arrow_forwardCaffeine prolongs the life span of acetylcholine molecules in the motor junctions. Explain how this fact is related to caffeine’s tendency to cause jitters, such as hand tremors and other small involuntary contractions.arrow_forwardWhat happens to acetylcholine after it evoked action of nicotinic acetylcholine receptors in the neuromuscular junction?arrow_forward
- When the neurotransmitter acetylcholine (ACh) binds the acetylcholine receptor (a GPCR) on muscle cells, it causes them to contract. ZIGGY, a chemical analog of ACh, also binds to the same acetylcholine receptor on muscle cells, but instead causes the muscle cells to relax. For this reason, it is sometimes prescribed as a muscle relaxer. Explain in 3-4 sentences how ZIGGY could cause muscle relaxation. How can both ZIGGY and ACh bind the same GPCR? And then how can they have different effects on the cells, despite binding to the same receptor on the same cells?arrow_forwardWhat is the significance of CNS and PNS. What is the significance of the neurotransmitter release at the neuromuscular junction and their action.arrow_forwardWhy is it important to remove acetylcholine from its binding to acetylcholine receptors once the neural stimulus ends? What can be the possible consequence of the non-removal of acetylcholine to the skeletal muscle fiber?arrow_forward
- hen an action potential arrives at the nerve terminal of a neuromuscular junction, which of the following statements best describes the events that occur? Depolarisation of the nerve terminal causes the release of ACh which activates nicotinic receptors on the skeletal muscle membrane to cause Ca2+ entry and muscle contraction. Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores causing the release of ACh which activates voltage-gated Na+ channels at the end-plate. Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores causing the release of ACh which binds to muscarinic receptors at the end plate. Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores…arrow_forwardThe drug Botox prevents wrinkles by preventing muscles from contracting. Specifically, it prevents acetylcholine from being released from the synaptic bulb. Explain how preventing acetylcholine prevents voluntary muscle contraction.arrow_forwardMotor neurons release what type of neurotransmitter onto the motor end plate of skeletal muscles? What effect does this neurotransmitter have on the postsynaptic membrane?arrow_forward
- A toxin produced by certain kinds of spiders increases the release of acetylcholine at the synaptic cleft. What effect do you think this action would have on muscle fibers?arrow_forwardWhat special characteristics of the presynaptic neuron (motor neuron) and motor end-plate (postsynaptic membrane in the NMJ) make it possible (and likely) that the threshold for an action potential will be reached in the muscle fiberarrow_forwardIn muscles, acetylcholine is released by the _________________________and opens specific channels that allow the ion ______ to depolarize the membrane. motor neuron, sodium motor neuron, potassium muscle fibril, sodium muscle fibril, potassiumarrow_forward
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