Chapter 11, Problem 11.39PP

a.

Summary Introduction

To determine:

The amino acid sequence for the given $\text{mRNA}$ portion: ${\text{5}}^{\prime }\text{CUU}\text{|}\text{AAA}\text{|}\text{CGA}\text{|}\text{GUU}{\text{3}}^{\prime }$

Introduction:

The genetic information in a nucleotide sequence is present in the form of codons. Each codon is a three base sequence in the $\text{mRNA}$ which codes for a specific amino acid. Amino acids are written as three letter code.

Mutation is a change in the nucleotide sequence of genetic material either due to the mistake in replication or due environmental factors.

b.

Summary Introduction

To determine:

The amino acid sequence if mutation changes CCU codon to the AUU codon and explain whether it will affect the protein function.

Introduction:

The genetic information in a nucleotide sequence is present in the form of codons. Each codon is a three base sequence in the $\text{mRNA}$ which codes for a specific amino acid. Amino acids are written as three letter code.

Mutation is a change in the nucleotide sequence of genetic material either due to the mistake in replication or due environmental factors.

c.

Summary Introduction

To determine:

The amino acid sequence if mutation changes CGA codon to the AGA codon and explain whether it will affect the protein function.

Introduction:

The genetic information in a nucleotide sequence is present in the form of codons. Each codon is a three base sequence in the $\text{mRNA}$ which codes for a specific amino acid. Amino acids are written as three letter code.

Mutation is a change in the nucleotide sequence of genetic material either due to the mistake in replication or due environmental factors.

d.

Summary Introduction

To determine:

The protein sequence if a mutation changes AAA to UAA.

Introduction:

The genetic information in a nucleotide sequence is present in the form of codons. Each codon is a three base sequence in the $\text{mRNA}$ which codes for a specific amino acid. Amino acids are written as three letter code.

Mutation is a change in the nucleotide sequence of genetic material either due to the mistake in replication or due environmental factors.

e.

Summary Introduction

To determine:

The protein sequence if an A is added to the beginning of the chain and the sequence changes to ${\text{5}}^{\prime }\text{ACU}\text{|}\text{UAA}\text{|}\text{ACG}\text{|}\text{AGU}{\text{3}}^{\prime }$.

Introduction:

The genetic information in a nucleotide sequence is present in the form of codons. Each codon is a three base sequence in the $\text{mRNA}$ which codes for a specific amino acid. Amino acids are written as three letter code.

Mutation is a change in the nucleotide sequence of genetic material either due to the mistake in replication or due environmental factors.

f.

Summary Introduction

To determine:

The protein sequence if C is removed from the beginning of the chain and the sequence changes to ${\text{5}}^{\prime }\text{UUA}\text{|}\text{AAC}\text{|}\text{GAG}{\text{3}}^{\prime }$.

Introduction:

The genetic information in a nucleotide sequence is present in the form of codons. Each codon is a three base sequence in the $\text{mRNA}$ which codes for a specific amino acid. Amino acids are written as three letter code.

Mutation is a change in the nucleotide sequence of genetic material either due to the mistake in replication or due environmental factors.