Biological Science (6th Edition)
6th Edition
ISBN: 9780321976499
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Emily Taylor, Greg Podgorski, Jeff Carmichael
Publisher: PEARSON
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Chapter 11, Problem 7TYU
QUANTITATIVE Suppose you were to model amplification by the phosphorylation cascade in Figure 11.16, using a penny for each kinase 1, a nickel for each kinase 2, and a dime for each kinase 3. Also suppose that Ras and each of the kinases can activate 10 proteins. How much money would you need to construct your model?
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Chapter 11 Solutions
Biological Science (6th Edition)
Ch. 11 - What is a fiber composite? How do cellular fiber...Ch. 11 - Prob. 2TYKCh. 11 - Prob. 3TYKCh. 11 - Prob. 4TYKCh. 11 - Prob. 5TYUCh. 11 - Summarize the experimental evidence in sponges...Ch. 11 - 7. QUANTITATIVE Suppose you were to model...Ch. 11 - What is the significance of the observation that...Ch. 11 - Prob. 9TYPSSCh. 11 - Prob. 10TYPSS
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- Describe the protein kinase cascade stimulated by epinephrine in liver cells or by insulin in muscle cells. How can it go wrong? What happens if it goes wrong? Explain the usefulness of protein kinase cascades and mechanisms to shut them down. Please give explanations for every step of this pathway. Define all technical terms you use.arrow_forwardWhat would be the effect of inhibiting the kinase?arrow_forwardDescribe HOW/WHY phosphorylation and de-phosphorylation act like an “on/off” switch for the relay molecules in a kinase cascade.arrow_forward
- Describe the 3 main steps for activation of receptor tyrosine kinases.arrow_forwardDiscuss Signaling by Receptors that Interact with Cytoplasmic Janus Kinases?arrow_forwardCompare and contrast GPCR and RTK signaling. What role does GTP play in each? What role does phosphorylation play? How is each signal differently amplified? How do these two signaling types compare to steroid signaling with respect to gene activation?arrow_forward
- Describe what cyclin dependent kinase does in the activation of MPF and how this relates to signal transduction.arrow_forwardCell signaling in plant and animal cells is similar in those ways and different in others. Offer one or more hypotheses for these similarities and differences, and cite specific examples.arrow_forwardcompare and contrast how GPCRs and RTKs transduce their signal to the cell? include the types of ligands they bind, the GTP binding protein that is activated, and how the signal is transduced and amplified. what effects does it have on the cell?arrow_forward
- Cite a metabolic pathway where active protein kinase is needed and explain its mechanism of action.arrow_forwardExplain, in detail, how tyrosine kinase proteins are involved in one signal transduction pathway of your choice. Make sure you describe the complete pathway in which it is involved. Then, describe how you would experimentally demonstrate the requirement of a tyrosine kinase protein in your chosen pathway.arrow_forwardWhen a signal binds to the Tyrosine kinase receptor (RTK), you have studied that a list of events occur sequentially. Map the events in the correct order from 1st to the last step.arrow_forward
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