EBK ESSENTIALS OF GENETICS
9th Edition
ISBN: 9780134190068
Author: Palladino
Publisher: YUZU
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Chapter 12, Problem 10PDQ
Why doesn't polynucleotide phosphorylase (Ochoa's enzyme) synthesize RNA in vivo?
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How does the archaeal RNA polymerase differ from that in Bacteria? How does the initiation of transcription in the two domains differ? Why do eukaryotic mRNAs have to be “processed” whereas most prokaryotic RNAs do not?
For the experiment outlined in Figure 15.8, could Nirenberg and Matthaei have substituted RNA polymerase instead of polynucleotide phosphorylase without otherwise modifying the experiment? Why or why not?
What factors account for the high phosphoryl-transfer potential of nucleoside triphosphates?
Chapter 12 Solutions
EBK ESSENTIALS OF GENETICS
Ch. 12 - CASE STUDY | A drug that sometimes works A...Ch. 12 -
CASE STUDY | A drug that sometimes works
A...Ch. 12 -
CASE STUDY | A drug that sometimes works
A...Ch. 12 - HOW DO WE KNOW? In this chapter, we focused on the...Ch. 12 - Review the Chapter Concepts list on p. 215. These...Ch. 12 - In studies of frameshift mutations, Crick,...Ch. 12 -
4. The mRNA formed from the repeating...Ch. 12 - In studies using repeating copolymers, AC......Ch. 12 - Prob. 6PDQCh. 12 - Prob. 7PDQ
Ch. 12 -
8. When the amino acid sequences of insulin...Ch. 12 - Prob. 9PDQCh. 12 - Why doesn't polynucleotide phosphorylase (Ochoa's...Ch. 12 - Refer to Table 12.1. Can you hypothesize why a...Ch. 12 -
12. Predict the amino acid sequence produced...Ch. 12 - A short RNA molecule was isolated that...Ch. 12 - A glycine residue exists at position 210 of the...Ch. 12 - Shown here is a theoretical viral mRNA sequence...Ch. 12 -
16. Most proteins have more leucine than...Ch. 12 - Define the process of transcription. Where does...Ch. 12 - Describe the structure of RNA polymerase in...Ch. 12 - In a written paragraph, describe the abbreviated...Ch. 12 - Messenger RNA molecules are very difficult to...Ch. 12 - One form of posttranscriptional modification of...Ch. 12 - In a mixed copolymer experiment, messages were...Ch. 12 -
23. Shown in this problem are the amino acid...Ch. 12 - Alternative splicing is a common mechanism for...Ch. 12 - The genetic code is degenerate. Amino acids are...
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- How do guanine and adenine nucleotides inhibit their own synthesis? How do they promote synthesis of each other?arrow_forwardMatch the following antibiotics with the drug strategy that would provide resistance to them. rifampin which blocks transcription [ Choose ] Choose] tetracycline which misaligns the beta-lactamase anticodon to its codon mutation of the TRNA binding site of the ribosome penicillin which blocks peptidoglycan creation of alternate metabolic pathway that ultimately leads to the same product synthesis mutation of RNA polymerase polymyxin which causes leakage in the porin which removes drug from periplasmic space cell membrane sulfonamide which inhibits enzyme of [Choose ] folic acid synthesis pathway Question 14 2 pts % & 5 7arrow_forwardWhat is the major difference between bacterial ribosomes and eukaryotic ribosomes that makes it possible to target bacterial ribosomes without harming our own cells?arrow_forward
- Which statement is true for the active site residues of RNase A, lysozyme, or trypsin? Select any/all answers that apply. O A. His12 (RNase A) initially acts as an acid. O B. His119 (RNase A) initially acts as an acid. O C. Glu35 (lysozyme) initially acts as an acid. O D. His57 (trypsin) initially acts as an acid. O E. Ser195 (trypsin) initially acts as an acid.arrow_forwardwhat is the nature and likely location(s) of a mutant that would, 1)allow constitutive expression of the lac gene? 2)prevent the cell from responding to lactose ( genes are not induced when exposed to lactose)? 3) not allow the cell to utilize lactose even when the genes are inducedarrow_forwardRifampicin attaches to the β subunit of bacterial RNA pol. Why is this used as an antibiotic to treat diseases caused by bacteria?arrow_forward
- Why can it be said that transcription of thebacteriophage T7 genome requires two enzymes?arrow_forwardWhat properties allow RNA molecules to act as catalysts?arrow_forward1) It is declared that some ribozymes are tightly bound to proteins. What isn't the function of those proteins? Select one: A) Regulate the enzymatic activities of the ribozyme B) Conduct the enzymatic function of the ribozyme C) Help the RNA fold properly D) Stabilize the RNA and the ribozyme 2) What promotes the histone chaperone - CAF-I aggregation to the replication machinery? Select one: A) Nucleosome tall modification B) sliding DNA clamp C) Clamp Loader D) DNA polymerasearrow_forward
- Which enzyme catalyzes the joining of deoxyribonucleotide triphosphates (dNTPs) in E. Coli? O a) RNA polymerase II b) DNA polymerse I O c) DNA polymerase III O d) Helicasearrow_forwardHow many RNA POLERASE(s) are found in prokaryotes, name and discuss their functions? proper explanation and diagramarrow_forwardWhat property of RNA makes it suitable for use as a ribozyme? For what reason do organisms not produce enough DNA enzymes?arrow_forward
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