Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+)
2nd Edition
ISBN: 9780137533114
Author: Dean Appling, Spencer Anthony-Cahill
Publisher: PEARSON+
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Textbook Question
Chapter 12, Problem 16P
How many ATP equivalents are consumed in the conversion of each of the following to a glucosyl residue in glycogen?
- Dihydroxyacetone phosphate
- Fructose-1 ,6-bisphosphate
- Pyruvate
- Glucose-6-phosphate
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In which of the following metabolic conversions is ATP “generated” during glycolysis?
Phosphoenolpyruvate -> pyruvate
2-Phosphoglycerate —> Phosphoenolpyruvate
Glucose-6-phosphate —> Fructose-6-phosphate
Fructose-1,6-bisphosphate —> Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate
Fructose-6-phosphate —> Fructose-1,6-bisphosphate
What glycolytic intermediate is fructose converted to in the muscle, such that it can be utilized in glycolysis?
Glucose 6-phosphate
Fructose 6-phosphate
Glyceraldehyde 3-phosphate
Dihydroxyacetone phosphate
In which of the following metabolic conversions is ATP “generated” during glycolysis?
Glucose —> Glucose-6-phosphate
1,3-Bisphosphoglycerate —> 3-Phosphoglycerate
Fructose-1,6-bisphosphate —> Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate
Glucose-6-phosphate —> Fructose-6-phosphate
2-Phosphoglycerate —> 3-Phosphoglycerate
Chapter 12 Solutions
Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+)
Ch. 12 - Prob. 1PCh. 12 - Methanol is highly toxic, not because of its own...Ch. 12 - Prob. 3PCh. 12 - Prob. 4PCh. 12 - Prob. 5PCh. 12 - Write balanced chemical equations for each of the...Ch. 12 - Prob. 7PCh. 12 - Prob. 8PCh. 12 - Prob. 9PCh. 12 - Prob. 10P
Ch. 12 - Some anaerobic bacteria use alternative pathways...Ch. 12 - Write a pathway leading from glucose to lactose in...Ch. 12 - Prob. 13PCh. 12 - Prob. 14PCh. 12 - Prob. 15PCh. 12 - How many ATP equivalents are consumed in the...Ch. 12 - Prob. 17PCh. 12 - Avidin is a protein that binds extremely tightly...Ch. 12 - 14CO2 was bubbled through a suspension of liver...Ch. 12 - Prob. 20PCh. 12 - Prob. 21PCh. 12 - Prob. 22PCh. 12 - Prob. 23PCh. 12 - 24. Glycogen synthesis and breakdown are regulated...Ch. 12 - Prob. 25PCh. 12 - Prob. 26PCh. 12 - Prob. 27PCh. 12 - Prob. 28PCh. 12 - 29 [1-14C] Ribose-5-phosphate is incubated with a...Ch. 12 - Prob. 30PCh. 12 - Prob. 31PCh. 12 - Prob. 32PCh. 12 - Prob. 33P
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- How many ATP are produced from a triglyceride containing three 14 carbon fatty acids? NOTE: Assume that glycerol is converted to Glyceraldehyde-3-Phosphate (step 6 of glycolysis).arrow_forwardThe complete oxidation of glucose 6-phosphate derived from free glucose yields 30 molecules ATP, whereas the complete oxidation of glucose 6- phosphate derived from glycogen yields 31 molecules of ATP. Account for this difference.arrow_forwardGlycogen synthase may be regulated by covalent modification and/or allosteric control. Label the diagram with the appropriate terms to describe glycogen synthase regulation. Use the following options: Glucose-6-Phospate; Insulin; Fructose-2,6-Bisphosphate; Phosphorylation, Dephosphorylationarrow_forward
- Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate carboxylase, to be the primary target for the regulation of gluconeogenesis at the level of control of enzyme synthesis? Match the words in the left column to the appropriate blanks in the sentences on the right. fructose-1,6-bisphosphate pyruvate 3-phosphoglycerate increasing reducing glycolytic pathway forward acetaldehyde lactate phosphoenolpyruvate oxaloacetate citric acid cycle back glyceraldehyde- 3-phosphate Firstly, pyruvate carboxylase converts which can participate in the gluconeogenesis pathway, and also plays an additional metabolic role in aiding the entry of intermediates into the Hence, it makes sense for phosphoenolpyruvate carboxykinase (PEPCK) to catalyze the conversion of gluconeogenesis pathway , thereby pyruvate carboxylase. to to Thirdly, PEPCK action results in the formation of amino acids and their subsequent entry into the citric acid cycle. Reset Help to push the…arrow_forwardWhat would be the effect (promotes glycolysis or gluconeogenesis) of a sudden increase in the concentration of (a) [ATP] ↑ (b) [AMP] ↑ (c) [fructose-1,6-bisphosphate] ↑arrow_forwardAt normal to low blood glucose concentrations (1.e., roughly 110 mg/dl or less), the enzyme that is responsible for sequestering or trapping glucose within cells is which of the following enzymes? O hexokinase O glycogen synthase O glucose-6-phosphatase O glucokinasearrow_forward
- Why is acetyl phosphate considered an energy-richcompound while glucose 6-phosphate is not?arrow_forwardThe coenzyme NAD+ is required for which glycolytic reaction shown below? Oglyceraldehyde-3-P→ 1,3-bisphosphoglycerate glucose glucose-6-P fructose-6-P→ fructose-1,6-BP 2-phosphoglycerate → phosphoenolpyruvatearrow_forwardIn metabolism, glucose-6-phosphate (G6P)can be used for glycogen synthesis or for glycolysis, among otherfates. What does it cost, in terms of ATP equivalents, to storeG6P as glycogen, rather than to use it for energy in glycolysis?Hint: The branched structure of glycogen leads to 90% of glucose residues being released as glucose-1-phosphate and 10%as glucose.arrow_forward
- How many ATP equivalents are consumed in the conversion of each of the following to a glucosyl residue in glycogen? (a) Dihydroxyacetone phosphate (b) Fructose-1,6-bisphosphate (c) Pyruvate (d) Glucose-6-phosphatearrow_forwardWhat enzyme will not be used if the oxidative portion of the pentose phosphate pathway is operating to produce ribose 5-phosphate? Ribulose 5-phosphate isomerase 6-phosphoglucono-lactonase 6-phosphogluconate dehydrogenase Transaldolasearrow_forwardMyristoleic acid is a monounsaturated fatty acid found in small amounts in a variety of foods. Calculate the net ATP yield from the complete β-oxidation of myristoleic acid. The formula of myristoleic acid is shown below (it is assumed that the total ATP production is the same for both saturated and unsaturated fatty acids having the same carbon chain length). CH3-(CH2)3-CHCH-(CH2)7-COOH (Given: The oxidation of one NADH yields 2.5 ATP; the oxidation of one FADH2 yields 1.5 ATP; and the oxidation of one acetyl CoA yields 10 ATP. ) Group of answer choices a. 96 ATP b. 92 ATP c. 94 ATP d. 34 ATP e. 36 ATParrow_forward
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