A&P INTEG APPRCH LL
4th Edition
ISBN: 9781266242748
Author: McKinley
Publisher: MCG
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Question
Chapter 12, Problem 3CSL
Summary Introduction
To determine:
The certain type of channel which is impaired by neurotoxins.
Concept introduction:
The neurotoxin is a type of toxin which affects the nervous tissues. Neurotoxin belongs to the class of exogenous chemical that adversely affects the functioning and structure of the nervous system. It will affect the functioning of both mature and developing nervous system. This neurotoxin prevents the depolarization stage of an action potential.
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A neurotoxin was delivered to a patient that prevented sodium channels from opening at the axon level. How does this affect a neuron's ability to communicate to other neurons? Explain in terms of action potential conductance, and neurotransmitter exocytosis at the axon terminal.
What would happen if the drug blocked K+ channels instead?
Identify the charges
(positive/negative) that appear on
the inside AND the outside of an axon while at resting
state.
Explain 2 factors that contribute to the maintenance of
this resting state.
Chapter 12 Solutions
A&P INTEG APPRCH LL
Ch. 12.1 - Prob. 1WDYLCh. 12.1 - Prob. 2WDYLCh. 12.1 - Prob. 3WDYLCh. 12.2 - Prob. 4WDYLCh. 12.2 - Prob. 5WDYLCh. 12.2 - Prob. 6WDYLCh. 12.2 - Prob. 7WDYLCh. 12.2 - Prob. 8WDYLCh. 12.3 - Prob. 9WDYLCh. 12.4 - If a person has a brain tumor, is it more likely...
Ch. 12.4 - Prob. 11WDYLCh. 12.4 - Prob. 12WDYLCh. 12.4 - Prob. 13WDYLCh. 12.5 - Prob. 14WDYLCh. 12.5 - Prob. 15WDYLCh. 12.6 - Prob. 16WDYLCh. 12.6 - Prob. 17WDYLCh. 12.7 - Prob. 18WDYLCh. 12.7 - Prob. 19WDYLCh. 12.7 - Prob. 20WDYLCh. 12.8 - How are EPSP and IPSP graded potentials...Ch. 12.8 - Prob. 22WDYLCh. 12.8 - How does depolarization and repolarization occur...Ch. 12.8 - Prob. 24WDYLCh. 12.8 - Prob. 25WDYLCh. 12.9 - Prob. 26WDYLCh. 12.9 - Prob. 27WDYLCh. 12.9 - Prob. 28WDYLCh. 12.10 - Prob. 29WDYLCh. 12.10 - Prob. 30WDYLCh. 12.10 - Prob. 31WDYLCh. 12.11 - Prob. 32WDYLCh. 12.11 - Prob. 33WDYLCh. 12 - Prob. 1DYKBCh. 12 - Prob. 2DYKBCh. 12 - Prob. 3DYKBCh. 12 - Prob. 4DYKBCh. 12 - Prob. 5DYKBCh. 12 - Prob. 6DYKBCh. 12 - _____ 7. An action potential is generated when...Ch. 12 - Prob. 8DYKBCh. 12 - Prob. 9DYKBCh. 12 - Prob. 10DYKBCh. 12 - What are the four structural types of neurons? How...Ch. 12 - Prob. 12DYKBCh. 12 - How does myelination differ between the CNS and...Ch. 12 - Describe the procedure by which a PNS axon may...Ch. 12 - Prob. 15DYKBCh. 12 - Prob. 16DYKBCh. 12 - Explain summation of EPSPs and IPSPs and the...Ch. 12 - Graph and explain the events associated with an...Ch. 12 - Prob. 19DYKBCh. 12 - Prob. 20DYKBCh. 12 - Prob. 1CALCh. 12 - Prob. 2CALCh. 12 - Prob. 3CALCh. 12 - Prob. 4CALCh. 12 - Sarah wants to call her new friend Julie and needs...Ch. 12 - Over a period of 6 to 9 months, Marianne began to...Ch. 12 - Prob. 2CSLCh. 12 - Prob. 3CSL
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The difference between the channels along the axon and the channels in the axon terminal is that? a) axon channels are voltage-gated sodium channels and axon terminal channels are voltage-gated calcium channels b) there is no difference c) axon channels are voltage-gated sodium channels and axon terminal channels are ligand- gated sodium channelsarrow_forwardWhen proteins are needed in the presynaptic terminal, they must be made in the neurosoma, which is sometimes far away and transported down the axon to the terminal. Why do you think they cannot simply be made locally, in the terminal itself?arrow_forwardThe Structure of the acetylcholine receptor is shown below: C. What type of channel is the acetylcholine receptor and what activates it?arrow_forward
- Let’s say the synapses of a neuron’s dendrites are filled with glutamate-gated channels which, when activated by glutamate, cause an excitatory postsynaptic potential (EPSP) in the neuron. In one instance, glutamate is released at all of the synapses simultaneously and this leads to an action potential in the neuron. A) What type of summation of PSPs is this? Why? B) List the sequence of steps that occur starting from binding of glutamate to the glutamate-gated channels at the synapses and ending with the membrane potential at the axon hillock returning to resting potential at the end of the action potential. (Include all the changes in voltage-gated channels underlying the action potential.)arrow_forwardHow do proteins and other chemicals synthesized in the soma get to the axon terminals? By what process can a virus that invades a peripheral nerve fiber get to the soma of that neuron?arrow_forwardAfter discussing his case with his physician, he learned that he had probably been the victim of pufferfish poisoning. The active toxin in the tissues of this fish is a chemical called tetrodotoxin (TTX). Tetrodotoxin is in a class of chemicals known as neurotoxins because it exerts its effects on neurons. The specific action of tetrodotoxin is that it blocks voltage-gated sodium ion channels. Define the following phrases and terms associated with the signs and symptoms of Dr. Westwood’s TTX poisoning: diaphoresis motor dysfunction paresthesias cyanotic hypoventilating bradycardia gastric lavage oxygen saturation As mentioned in the case description, tetrodotoxin is a molecule that blocks voltage-gated sodium ion channels. What is a voltage-gated sodium ion channel and what is its function? When nerve cells are at rest, there is an unequal amount of positive and negative charges on either side of a nerve cell membrane. This charge difference creates an electrical potential.…arrow_forward
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