A&P INTEG APPRCH LL
4th Edition
ISBN: 9781266242748
Author: McKinley
Publisher: MCG
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Chapter 12.8, Problem 25WDYL
Summary Introduction
To determine:
The sequence of events from the arrival of an action potential at the synaptic knob until the release of neurotransmitter into the synaptic cleft.
Concept introduction:
A neurotransmitter is chemical substances which are released by the axon terminals at the time of arrival of the nerve impulses. These neurotransmitters are stored in synaptic vesicles. These vesicles then fuse with the sending membrane which results in the release of neurotransmitter into the synaptic cleft.
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Students have asked these similar questions
What triggers neurotransmitter release at the synaptic cleft?
Which of the following statements about action potentials and information transmission in the synaptic cleft is FALSE?
1. Action potentials determine the amount of neurotransmitters that are released into the synaptic cleft
2.Action potentials ultimately result in more calcium leaving the target cell at the postsynaptic membrane
3. Action potentials determine the duration that neurotransmitters are released into the synaptic cleft
4. Action potentials ultimately result in more calcium entering the neuron at the axon terminal
Given the steps shown below, which of the following is the correct sequence for transmission at a
chemical synapse?
1. neurotransmitter binds with receptor
2. sodium ions rush into neuron's cytoplasm
3. action potential depolarizes the presynaptic membrane
4. ion channel opens to allow particular ion to enter cell
5. synaptic vesicles release neurotransmitter into the synaptic cleft
O 1, 2, 3, 4, 5
O 5, 1, 2, 4, 3
O 2, 3, 5, 4, 1
O4, 3, 1, 2, 5
O 3, 2, 5, 1, 4
Chapter 12 Solutions
A&P INTEG APPRCH LL
Ch. 12.1 - Prob. 1WDYLCh. 12.1 - Prob. 2WDYLCh. 12.1 - Prob. 3WDYLCh. 12.2 - Prob. 4WDYLCh. 12.2 - Prob. 5WDYLCh. 12.2 - Prob. 6WDYLCh. 12.2 - Prob. 7WDYLCh. 12.2 - Prob. 8WDYLCh. 12.3 - Prob. 9WDYLCh. 12.4 - If a person has a brain tumor, is it more likely...
Ch. 12.4 - Prob. 11WDYLCh. 12.4 - Prob. 12WDYLCh. 12.4 - Prob. 13WDYLCh. 12.5 - Prob. 14WDYLCh. 12.5 - Prob. 15WDYLCh. 12.6 - Prob. 16WDYLCh. 12.6 - Prob. 17WDYLCh. 12.7 - Prob. 18WDYLCh. 12.7 - Prob. 19WDYLCh. 12.7 - Prob. 20WDYLCh. 12.8 - How are EPSP and IPSP graded potentials...Ch. 12.8 - Prob. 22WDYLCh. 12.8 - How does depolarization and repolarization occur...Ch. 12.8 - Prob. 24WDYLCh. 12.8 - Prob. 25WDYLCh. 12.9 - Prob. 26WDYLCh. 12.9 - Prob. 27WDYLCh. 12.9 - Prob. 28WDYLCh. 12.10 - Prob. 29WDYLCh. 12.10 - Prob. 30WDYLCh. 12.10 - Prob. 31WDYLCh. 12.11 - Prob. 32WDYLCh. 12.11 - Prob. 33WDYLCh. 12 - Prob. 1DYKBCh. 12 - Prob. 2DYKBCh. 12 - Prob. 3DYKBCh. 12 - Prob. 4DYKBCh. 12 - Prob. 5DYKBCh. 12 - Prob. 6DYKBCh. 12 - _____ 7. An action potential is generated when...Ch. 12 - Prob. 8DYKBCh. 12 - Prob. 9DYKBCh. 12 - Prob. 10DYKBCh. 12 - What are the four structural types of neurons? How...Ch. 12 - Prob. 12DYKBCh. 12 - How does myelination differ between the CNS and...Ch. 12 - Describe the procedure by which a PNS axon may...Ch. 12 - Prob. 15DYKBCh. 12 - Prob. 16DYKBCh. 12 - Explain summation of EPSPs and IPSPs and the...Ch. 12 - Graph and explain the events associated with an...Ch. 12 - Prob. 19DYKBCh. 12 - Prob. 20DYKBCh. 12 - Prob. 1CALCh. 12 - Prob. 2CALCh. 12 - Prob. 3CALCh. 12 - Prob. 4CALCh. 12 - Sarah wants to call her new friend Julie and needs...Ch. 12 - Over a period of 6 to 9 months, Marianne began to...Ch. 12 - Prob. 2CSLCh. 12 - Prob. 3CSL
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- When an impulse arrives at the synapse, the synaptic vesicles open and release neurotransmitters into the cleft within a thousandth of a second. Within another ten thousandth of a second, these molecules have diffused across the cleft and bound to receptor sites in the effector cell. In what two ways is transmission across a synapse terminated so that the neuron’s signal is concluded?arrow_forwardArrange the events that occur during synaptic transmission. Use letters A-F to denote the correct sequence. Use the diagram on the right as a clue. Example: SENDING NEURON B 1. lon channel opens Synepto SYNAPSE 1. lon channel opens 2. Neurotransmitter is released into synaptic cleft SYNAPTIC CLEFT RECEVING HEURC4 Neurotransmitter 3. Vesicle fuses with plasma membrane Jon chennels Neurotransmtter Reseptor deurotranemitter brohen down and sa sd 4. Neurotransmitter binds to receptor BOns 前 命 5. Action potential arrives 6. lon channel closes the obeicos in the bo y belo M (A narrow_forwardhow many molecules of neurotransmitter are in a synaptic vesicle?arrow_forward
- Which types of patch clamp technique should be used if you want to determine if a particular compound is influencing synaptic transmission presynaptically or post synaptically?arrow_forwardHow the pre-synaptic neuron transmits an impulse (action potential) across the synaptic cleft to the post-synaptic neuron?arrow_forwardIf action potential propagation from one neuron to another neuron requires ACh release, what event at the synaptic cleft explains the need for action potentials to arrive at a high rate before the post-synaptic membrane achieves threshold? the lack of sodium voltage gated channels on the post-synaptic membrane O the rapid breakdown of ACh by ACHE at the synaptic cleft the slow release of ACh by the synaptic vessicles the slow movement of sodium through chemical gates Previous Next MacBook Airarrow_forward
- If an excitatory neurotransmitter binds to the post-synaptic neuron, what type of an event will that cause? What happens if the neurotransmitter is an inhimitory neurotransmitter? What type of ion will move into the post-synaptic neuron? What type of polarizing event will occur? and What happen at the axon hillock?arrow_forwardHow is synaptic transmission terminated in the synapse or at the terminal button?arrow_forwardWhat are the criteria for identification of the neurotransmitter at a particular synapse? Which two criteria are sufficient to conclude that a candidate substance is a neurotransmitter?arrow_forward
- Which of the following is the role of axonal Calcium (Ca2+) channels in neuronal communication at the synapse? a) they inhibit the action potential causing it to stop b) Calcium channels have no role in this process c) by allowing calcium to exit the cell, they promote the propagation of action potential across the synapse by creating depolarization d) by blocking calcium entrance, they mediate the contraction of presynaptic axon to facilitate movement e) when they open, calcium enters the presynaptic terminal, promoting fusion of neurotransmitter vesicles with presynaptic membrane, and release of neurotransmitters to the synaptic cleftarrow_forwardWhat is synaptic cleft ?arrow_forwardIf a pre-synaptic cell releases a large amount of excitatory neurotransmitter into the synaptic cleft, how will that affect the PSPs? Does that large release ensure that the postsynaptic cell will initiate an action potential, and what role does the axon hillock play in this process/decision?arrow_forward
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