Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
Question
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Chapter 13, Problem 12P
Interpretation Introduction

Interpretation:

Which one of the five steps of the a -ketoglutarate dehydrogenase complex reaction is metabollically unstable at physiological conditions?

Concept Introduction:

The five step of the five steps of the a -ketoglutarate dehydrogenase complex reaction are:

  1. Decarboxylation
  2. Oxidation of the 4-carbon group, reduction of lipoamide disulfide.
  3. Transacylation.
  4. Dihydrolipolyl dehydrogease.
  5. FADH2 is reoxidised by NAD+ to form NADH.

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