Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 13, Problem 12P
A normal chromosome and its homolog carrying a paracentric inversion are given. The dot (•) represents the centromere.
Normal ABC •DEFGHIJK
Inversion abc •djihgfek
Diagram the alignment of chromosomes during prophase I.
Assume a crossover takes place in the region between F and G. Identify the gametes that are formedfollowing this crossover, and indicate which gametes are viable.
Assume a crossover takes place in the region between A and B. Identify the gametes that are formed by this crossover event, and indicate which gametes are viable.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Changes in Chromosome Structure and Number
An inversion heterozygote has homologous chromosomes with the
following linkage arrangements:³
b
• а
b
e
a. What type of inversion is it?
b.
Draw the configuration of the chromosomes at synapsis of Prophase I.
a
с
f
d
e
d
f
с
g
c. If a four-strand double crossover occurs in the areas c-d (including
chromatids 2 and 3) and e-f (including chromatids 1 and 4), what are
the meiotic products?
d. Repeat for a three-strand double crossover c-d (chromatids 2 and 3),
and f-g (chromatids 1 and 3).
e. For both types of double crossovers will any of the meiotic products
be viable? If so which?
Inversions are known to affect crossing-over. The following homologs have the indicated order (the filled and open circles indicate centromeres):
• (A B C D E)
o (A D C B E)
b. Diagram the alignment of these chromosomes during meiosis.
An initial crossover event will occur between A and B, as indicated in the corresponding image. After this initial event occurs, a second crossover event occurs (not illustrated) involving the products of the first crossover event.
a. Given this chromosome organization, A B c, A b c, a B C, and a b C, which two chromatids of the bivalent were involved
chromatid 1
chromatid 2
chromatid 3
chromatid 4
and between which genes
gene A
gene B
gene C
did the second crossover event occur to produce the indicated chromosomes?
b. Returning to the original crossover depicted in the image, given this chromosome organization, A B C, A B C, a b c, and a b c, which two chromatids of the bivalent were involved
chromatid 1
chromatid 2
chromatid 3
chromatid 4
and between which genes
gene A
gene B
gene C
did the second crossover event occur to produce the indicated chromosomes?
Chapter 13 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 13 - Prob. 1PCh. 13 - For one set of chromosomes carried by a triploid...Ch. 13 - 10.8 If the haploid number for a plant species is...Ch. 13 - From the following list, identify the types...Ch. 13 - Mating between a male donkey (2n=64) and a female...Ch. 13 - Prob. 6PCh. 13 - Prob. 7PCh. 13 - What can we conclude about a mutational event...Ch. 13 - 9. In terms of the chromosome content of nuclei,...Ch. 13 - 10. In Drosophila, an X-linked recessive allele...
Ch. 13 - The plants in this problem are the same as those...Ch. 13 - A normal chromosome and its homolog carrying a...Ch. 13 - 10.12 A pair of homologous chromosomes in...Ch. 13 - 10.13 An animal heterozygous for a reciprocal...Ch. 13 - Dr. Ara B. Dopsis has an idea he thinks will be a...Ch. 13 - Suppose polymerase chain reaction (PCR) is used...Ch. 13 - Prob. 17PCh. 13 - A healthy couple with a history of three previous...Ch. 13 - A boy with Down syndrome (trisomy 21) has 46...Ch. 13 - Prob. 20PCh. 13 - 10.28 A small population of deer living on an...Ch. 13 - In humans that XX/XO mosaics, the phenotype is...Ch. 13 - 10.20 A plant breeder would like to develop the...Ch. 13 - In Drosophilia, seven partial deletion (1to7)...Ch. 13 - Two experimental varieties of strawberry are...Ch. 13 - 10.23 In the tomato, Solanum esculentum, tall ()...Ch. 13 - In Drosophila, the wild-type red eye color is...Ch. 13 - A DrosophilaPelement 2.5kb in length is modified...Ch. 13 - A biologist studying flight mechanisms in insects...Ch. 13 - 30. After reading Experimental Insight and...Ch. 13 - 31. Two NotI restriction enzymes cleave DNA on...Ch. 13 - For the following crosses, determine as accurately...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Chromosome structural errors can occur during Meiosis which can lead to health disorders. Examine the figure below and select the correct order of error type from left to right in which they appear. duplicati on, translocation, deleti on, inversion duplication, inversion, del etion, translocation O deletion, translocati on, inversion, duplication O translocation, inversion, duplication, deletion inversion, translocation, duplication, deletionarrow_forwardAn individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B ● C D E F G, A B • C D V W X, R S •T U E F G, R S•T U V W Xa. Draw the pairing arrangement of these chromosomes in prophase 1 of meiosis. Mention their gametic composition. b. Draw the alternate, adjacent I, and adjacent II segregation patterns in anaphase I of meiosis. Mention their gametic composition.arrow_forwardAn inversion heterozygote has the following inverted chromosome: Centromere ca a a A B CD JI HGF E, KL M Inverted region If a crossover occurred between genes H and I on one inverted and one normal chromosome, what would be the sequence of the dicentric chromosome before completion of metaphase I? A Cen B C D EFGHIJKL Cen M A Cen B C D JIHGFEKLM Cen JIH G F E Cen A Cen B C D JIHGFEDC B Cen A MLKEFGHIJKLMarrow_forward
- A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. Q. What types of zygotes will develop when each of gametes produced by the man fuses with a normal gamete produced by the woman?arrow_forwardn corn, male sterility is controlled by maternal cytoplasmic elements. This phenotype renders the male part of the corn plants (i.e the tassel) unable to produce fertile pollen; the female parts, however, remain receptive to pollination by pollen from male fertile corn plants. However, the presence of a nuclear fertility restorer gene F restores fertility to male sterile lines sing the cardboard chips, simulate the crosses indicated below. Give the genotypes and phenotypes of the offsprings in each cross, and properly label the nucleus and the cytoplasm of each individual in the cross Legend male sterile cytoplasm Male fertile cytoplasm FF nucleus Ff nucleus ff nucleus A. Male sterile female x FF male Explain the phenotype of the offspring B. Male sterile female x Ff male Explain the phenotype of the offspringarrow_forwardwhy two crossovers are needed on one chromatid arm? explain pleasearrow_forward
- Here is a depiction of the position of several genes on 2 chromosomes, with a dash "-" depicting the position of the centromere. Chromosome A has genes ABCD-EFGHIJ Chromosome B has genes 1234-56789. Please name the kind of rearrangement that would result in the following derivative chromosomes: 12D-EFGHIJ AB4-56789 O Unbalanced reciprocal translocation Unbalanced nonreciprocal translocation Balanced reciprocal translocation Balanced nonreciprocal translocationarrow_forwardThe STR DNA marker DS11 is located on the p arm of the chromosome #8 in humans. Molecular analysis has shown that Charlie Chaplin is a heterozygote for the STR marker (genotype DS11A and DS11B) Using this knowledge, provide a diagram of meiosis showing only the movements of chromosome 8 (assume no nondisjunction). Throughout, indicate where the marker may be found (in other words, label the chromosome to show where the STR markers can be found. (Show ONLY the chromosomes at interphase, metaphase 1, end of meiosis 1, metaphase 2, and end of meiosis 2). Suppose Charlie conceived a son with a chromosome 8 trisomy. Molecular analysis of the STR DS11 marker revealed that his son carried two copies of the DS11A marker and a DS11C marker. Based on the data, determine if the nondisjunction occurred in Charlie or in the mother? Provide your reasoning.arrow_forwardA diploid species has 3 pairs of chromosomes in its somatic cells. In males, the first pair is large submetacentric[1]; the second is medium acrocentric[2], and the third is small telocentric[3]. In females, the first two pairs are like those of the males while the third is large metacentric[4][5], with satellite4 Illustrate the karyograms (drawing/picture of the chromosome) of the following: A triploid cell in females tetrasomic cell in males tetraploid cell in females [1] submetacentric --centrosome is just above the middle of the chromosome [2] acrocentric --centrosome is much higher location than submetacentric so that the “p” arm of the chromosome is much shorter than the q arm [3] telocentric --the centromere is at the end of the chromosome [4] metacentric --centrosome is in the middle of the chromosome; thus the “p-arm” and the “q-arm” or both arms of the chromosome are equal in length [5] satellite-a constriction in an arm of a chromosome, aside…arrow_forward
- A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. Q. List all the different types of gametes that might be produced by the man.arrow_forwardWhat are the chromosome configuration that will be observed at diakinesis in the following situation/mutation, given a hypothetical organism with chromosome number, 2n = 10? 1. Trisomic for chromosome 5 2. Tetrasomic for chromosome 4 3. Nullisomic for chromosome 2 4. Double monosomic for chromosomes 1 and 2 5. Monoploid Match with the following chromosome configuration and pls. explain. A. 1 IV + 4 II B. 2I + 3 II C. 1 IV +4 II D. 4 II E. 5 Iarrow_forwardTwo chromosomes have the ff. order of genes: Normal A B centromere C D E F G H I Abnormal a b centromere g f e d c h i a. Does the abnormal chromosome have a pericentric or paracentric inversion? Why? b. Draw a sketch to show how these two chromosomes (duplicated) would pair during synapsis. Assume a CO will occur between genes E and F. What gametes are ultimately formed at the end of telophase II and describe.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Genetic Variation and Mutation | 9-1 GCSE Science Biology | OCR, AQA, Edexcel; Author: SnapRevise;https://www.youtube.com/watch?v=bLP8udGGfHU;License: Standard YouTube License, CC-BY