The strain of bacteria that entered normal epithelial cells most easily. Concept introduction: Allele is the modification of the gene. Salmonella typhi is the causative bacteria of typhoid. Cystic fibrosis (CF) is a genetic disorder due to inability of the cell to perform endocytosis due to mutation in the CFTR gene. Cystic fibrosis affects the lungs, intestine, liver, and kidneys. Endocytosis is a phenomenon where the cell takes up molecules by engulfing with its membrane. The S. typhi exploits this mechanism to infect the intestinal cell and causes diarrhea. The cells that are homozygous for this CFTR mutation cannot perform endocytosis, and the S. typhi cannot infect those individuals.

Question

Want to see the full answer?

Answer 1

Question

Chapter 13, Problem 2DAA

Summary Introduction

To explain: The strain of bacteria that entered normal epithelial cells most easily.

Concept introduction: Allele is the modification of the gene. Salmonella typhi is the causative bacteria of typhoid. Cystic fibrosis (CF) is a genetic disorder due to inability of the cell to perform endocytosis due to mutation in the CFTR gene. Cystic fibrosis affects the lungs, intestine, liver, and kidneys. Endocytosis is a phenomenon where the cell takes up molecules by engulfing with its membrane. The S. typhi exploits this mechanism to infect the intestinal cell and causes diarrhea. The cells that are homozygous for this CFTR mutation cannot perform endocytosis, and the S. typhi cannot infect those individuals.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Daichi Yamada, 65 years old, immigrated to California to live with his son after the Fukushima tsunami and nuclear power plant disaster destroyed his community in 2011. Recently he began complaining of fatigue, left-side pain, abdominal fullness, and night sweats. His son scheduled a check-up for him, and a routine blood screening test showed elevated basophils and eosinophils. Bone marrow tests showed the Philadelphia chromosome by fluorescence in situ hybridization (FISH), confirming rearrangement between chromosomes 9 and 22, which occurs in 95% of cases of chronic myelogenous leukemia (CML). He also had an enlarged spleen and liver. A diagnosis of CML was made and treatment with the tyrosine kinase inhibitor imatinib mesylate (Gleevec) began. Over the next 4–8 weeks Daichi’s bone marrow showed regrowth of normal stem-cell populations, and stable white blood cell proportions were restored. Which of the following genes are associated with the chromosomal translocation in CML? a.…

. Mutations in an autosomal gene in humans cause aform of hemophilia called von Willebrand disease(vWD). This gene specifies a blood plasma proteincleverly called von Willebrand factor (vWF). vWFstabilizes factor VIII, a blood plasma protein specified by the wild-type hemophilia A gene. Factor VIIIis needed to form blood clots. Thus, factor VIII is rapidly destroyed in the absence of vWF.Which of the following might successfully be employed in the treatment of bleeding episodes in hemophiliac patients? Would the treatments workimmediately or only after some delay needed forprotein synthesis? Would the treatments have only ashort-term or a prolonged effect? Assume that allmutations are null (that is, the mutations result in thecomplete absence of the protein encoded by the gene)and that the plasma is cell-free.a. transfusion of plasma from normal blood into avWD patientb. transfusion of plasma from a vWD patient into adifferent vWD patientc. transfusion of plasma from a hemophilia A…

An acute leukemia patient presents with blast morphology that is of neutrophil lineage with Auer rods and pseudo−Pelger-Huët nuclei, myeloperoxidase, and Sudan Black B. Cytogenetic analysis reveals a t(8;21)(q22;q22) translocation in the majority of the blasts. Which classification of AML best fits this morphology, immunophenotyping, and cytochemistry? Select one: a.AML with recurrent genetic abnormalities b.AML with multilineage dysplasia c.AML, therapy-related d.AML not otherwise categorized