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Concept explainers
Interpretation:
The fate of each labeled carbon in pyruvate labeled with with carbon 1 (carboxyl), carbon 2 (carbonyl), and carbon 3 (methyl) during one turn of the citric acid cycle should be determined.
Concept Introduction:
The pyruvate from glycolysis enters the citric acid cycle for the complete breakdown of glucose molecule which gets first catalyzed by acetyl CoA to produce citrate and then isocitrate which gets oxidized to 2- oxoglutarate which produces succinate through succinyl CoA. Finally, oxaloacetate is produced through malate which gets produced from fumarate or fumaric acid.
Pictorial representation:
The citric acid cycle can be represented in a pictorial manner as:
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Chapter 13 Solutions
Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+)
- BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. FreemanLehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. FreemanFundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningFundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON
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