To describe:
The way by which DNA microarrays and DNA sequencing could be used to identify the defective gene
Introduction:
A DNA microarray is a great invention as it allows for the comparison of thousands of genes at one time.The technology uses chips with attached DNA sequences as probes for gene expression. Any DNA in the sample that is complementary to a probe sequence will get bound to the chip. This technology is useful when used on known species with a sequenced genome.
Answer to Problem 31A
DNA sequencing allows scientists to find out the position of the faulty gene or mutation in the genome.
DNA microarrays help in analyzing the expression of the defective gene.
Explanation of Solution
DNA sequencing is done by creating fragments of DNA by using restriction enzymes. The fragments are then combined with vectors to create recombinant DNA. These are then cloned to make multiple copies and are sequenced using automated machines. DNA can be sequenced using fluorescent tagged
Chapter 13 Solutions
Biology Illinois Edition (Glencoe Science)
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