Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN: 9781305073951
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 14, Problem 1GP
Summary Introduction
To explain: Duchenne muscular dystrophy occurs almost exclusively in males.
Introduction:
Duchenne muscular dystrophy (DMD) is a genetic disorder caused by the mutation of the dystrophin gene. It is located on X chromosome. The dystrophin protein is found in the skeletal and cardiac muscles that provide strength to muscle fibers and connect cytoplasm in the muscle cells to the extracellular matrix. The mutation in the gene results in defective dystrophin protein causing muscle degeneration. DMD is a recessive X-linked condition.
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Duchenne muscular dystrophy, which is inherited in an X-linked recessive pattern, nearly always occurs in males. Explain why.
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Chapter 14 Solutions
Biology: The Unity and Diversity of Life (MindTap Course List)
Ch. 14 - Constructing a pedigree is particularly useful...Ch. 14 - Prob. 2SQCh. 14 - Prob. 3SQCh. 14 - Prob. 4SQCh. 14 - Prob. 5SQCh. 14 - A trait that is present in a male child but not in...Ch. 14 - Color blindness is a case of ______ inheritance....Ch. 14 - A female child inherits one X chromosome from her...Ch. 14 - Prob. 1DAACh. 14 - Prob. 2DAA
Ch. 14 - Prob. 3DAACh. 14 - Prob. 9SQCh. 14 - Expression of the SRY gene on the Y chromosome...Ch. 14 - Prob. 11SQCh. 14 - Prob. 12SQCh. 14 - Prob. 13SQCh. 14 - Prob. 14SQCh. 14 - Match the chromosome terms appropriately. ____...Ch. 14 - Prob. 1GPCh. 14 - Does the phenotype indicated by the red circles...Ch. 14 - Human females have two X chromosomes (XX); males...Ch. 14 - A mutated allele responsible for Marfan syndrome...Ch. 14 - The somatic cells of most individuals with Down...Ch. 14 - Mutations in the genes for clotting factor VIII...
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- Analysis of X-Linked Dominant and Recessive Traits As a genetic counselor investigating a genetic disorder in a family, you are able to collect a four-generation pedigree that details the inheritance of the disorder in question. Analyze the information in the pedigree to determine whether the trait is inherited as: a. autosomal dominant b. autosomal recessive c. X-linked dominant d. X-linked recessive e. Y-linkedarrow_forwardPhenylketonuria and alkaptonuria are both autosomal recessive diseases. If a person with PKU marries a person with AKU, what will the phenotype of their children be?arrow_forwardDoes the phenotype indicated by the red circles and squares in this pedigree show an inheritance pattern that is autosomal dominant, autosomal recessive, or X-linked?arrow_forward
- Huntington’s disease is an autosomal dominant disease in humans, but the first symptoms usually don’t appear until after the age of 30. If Aethelbert inherited one copy of this gene from his mother, what is the chance of him passing it on to his children?arrow_forwardBy looking at the following pedigree can you conclude why is it an X-linked recessive? If yes, why not dominant, Sex influenced, or Autosomal. Please provide sufficient reasoning, Thank you.arrow_forwardIf a man has an X-linked recessive disease, can his sons inherit that disease from him? Why or why not?arrow_forward
- Is this pedigree dominant or recessive. Which best defines this pedigree Autosomal or sex-linked?arrow_forwardThe following pedigree illustrates the inheritance of Nance–Horan syndrome, a rare genetic condition in which affected people have cataracts and abnormally shaped teeth.arrow_forwardVictoria’s youngest child, Beatrice, gave birth to one daughter, one normal son, and two hemophilic sons. **Based on the pedigree, Alfonso XIII of Spain is phenotypically normal. Does that mean he received the normal gene from Beatrice? Why or Why not?**arrow_forward
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