Concept explainers
We now continue the introduction of
To make your own reaction roadmap for Chapters 15–18, take a blank sheet of paper and write the following functional groups in the orientations shown. Fill the entire sheet of paper and leave plenty of room between functional groups. Most students find it helpful to use a poster-sized piece of paper filled out in landscape orientation.
Refer to the “Study Guide” section of this chapter. Draw arrows between functional groups to account for each reaction. Write the reagents required to bring about each reaction next to the arrow. Then record any regiochemistry or stereochemistry considerations relevant to the reaction. You should also record any key aspects of the mechanism, such as formation of a carbocation intermediate, as a helpful reminder. It is important to keep track of all reactions that make carbon-carbon bonds, because these will help you build large molecules from smaller fragments.
On the above organic chemistry reaction roadmap template, the information for the Simmons-Smith reaction, the seventh reaction in the “Study Guide” section has been added to help you get started. For this reaction roadmap, do not write an arrow for reactions 1, 2, and 4 explicitly, because these are considered reagents, which are prepared immediately prior to use. A reaction roadmap is used to indicate interconversion of molecules with more stable functional groups. Appendix 10 contains a series of roadmaps for different sections of the book, but you should use those for reference only after you have completed your own.
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Student Study Guide and Solutions Manual for Brown/Iverson/Anslyn/Foote's Organic Chemistry, 8th Edition
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- We now continue the use of organic chemistry reaction roadmaps. Because of the unique nature of the new reactions presented, we recommend that you make a new roadmap only for Chapters 2023. To make your own roadmap for Chapters 2023, take a blank sheet of paper and write the following functional groups in the orientations shown. Fill the entire sheet of paper and leave plenty of room between functional groups. Most students find it helpful to use a poster-sized sheet of paper filled out in landscape orientation. We now continue the use of organic chemistry reaction roadmaps. Because of the unique nature of the new reactions presented, we recommend that you make a new roadmap only for Chapters 2023. To make your own roadmap for Chapters 2023, take a blank sheet of paper and write the following functional groups in the orientations shown. Fill the entire sheet of paper and leave plenty of room between functional groups. Most students find it helpful to use a poster-sized sheet of paper filled out in landscape orientation.arrow_forwardWrite the products of the following sequences of reactions. Refer to your reaction roadmaps to see how the combined reactions allow you to navigate between the different functional groups. Note that you will need your old Chapters 611, Chapters 1518, and Chapter 19 roadmaps along with your new Chapter 20 reaction roadmap for these.arrow_forwardWrite the products of the following sequences of reactions. Refer to your reaction roadmaps to see how the combined reactions allow you to navigate between the different functional groups. Note that you will need your old Chapters 611, Chapters 1518, and Chapter 19 roadmaps along with your new Chapters 2021 roadmaps for these.arrow_forward
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- This question concerns adrenalin which is a hormone, a chemical messenger which stimulates the central nervous system. It's structure is shown below. It has a number of functional groups. What is a functional group? Identify and name the functional groups. Give the reagents and reaction conditions that establish the presence of any TWO of the functional groups present in adrenalinarrow_forwardFor Questions 1-20, Canvas will ask you to answer a random selection of 20 boxes. Cross-reference the column and row to predict the major reaction that will occur with that particular haloalkane and nucleophile. Be as accurate as possible! Your answers will be one of the following: SN2 E2 (for any Elimination reaction that only has one possible product) E2Z (for Zaitsev Elimination) E2H (for Hofmann Elimination) SN1 E1 NR (for No Reaction). Haloalkane CH3-CI CH3CH₂CH₂-CI CI CH3-CH-CH₂-CH3 CI CH3-C-CH₂-CH3 1 CH3 CH3-CH=CH-CH2 CI CH2=CH-C-CH3 CH3 5-5 CI CI CH CH3 CI CH₂ OT CI CH,CH,ONa, CH₂CH₂OH Box 1 Box 7 Box 13 Box 19 Box 25 Box 31 Box 37 Box 43 Box 49 Box 55 CH3CH₂OH . 0°C Box 2 Box 8 Box 14 Box 20 Box 26 Box 32 Box 38 Box 44 Box 50 Box 56 Reaction Conditions NaSH DMF CH3CH₂OH 60°C Box 3 Box 9 Box 15 Box 21 Box 27 Box 33 Box 39 Box 45 Box 51 Box 57 Box 4 Box 10 Box 16 Box 22 Box 28 Box 34 Box 40 Box 46 Box 52 Box 58 (CH3),CONa (CH3)3COH Box 5 Box 11 Box 17 Box 23 Box 29 Box 35 Box 41…arrow_forwardAcyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. CI + H₂N • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. OH • Do not include counter-ions, e.g., Na+, I¯, in your answer. • In cases where there is more than one answer, just draw one.arrow_forward
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning