BIOLOGY >PRINT UPGRADE<
11th Edition
ISBN: 9780357091586
Author: Solomon
Publisher: CENGAGE L
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Chapter 15, Problem 15TYU
EVOLUTION LINK DNA technology, such as the production of transgenic animals, is possible only because widely different organisms have essentially identical genetic systems (DNA→ RNA→ protein). What is the evolutionary significance of the universality of genetic systems in organisms as diverse as bacteria and pigs?
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In 1995, Hamilton Smith, Craig Venter and co-workers published the first complete genome sequence of a self-sustaining organism, that of the bacterium Haemophilus influenzae. Analysis of the genome sequence revealed that the organism does not have a gene that could encode a telomerase enzyme. What is the potential evolutionary consequence of this? Explain your answer.
Research has now demonstrated that techniques that have been developed for cloning animals could be used to clone human embryos, although no living human clones have been produced. There is widespread consensus that cloning a live human would be unethical. However, some people have suggested creating cloned embryos from which stem or pluripotent cells, which have the ability to develop into any tissue or organ, could be extracted. The stem and pluripotent cells might then be used to create genetically identical tissues and organs that could then be transplanted back into the donor to treat failed organs and diseases. What might be some reasons for or against this type of therapeutic cloning?
Chapter 15 Solutions
BIOLOGY >PRINT UPGRADE<
Ch. 15.1 - Prob. 1LOCh. 15.1 - Explain how gel electrophoresis is used to...Ch. 15.1 - Describe how PCR is used to amplify a specific...Ch. 15.1 - Compare the possible differences between a...Ch. 15.1 - Prob. 1CCh. 15.1 - Different forms of a protein are produced in the...Ch. 15.1 - What advantages does the PCR method have over gene...Ch. 15.2 - Describe the features of a typical CRISPR locus in...Ch. 15.2 - Explain the function of CRISPR in bacterial cells.Ch. 15.2 - Compare CRISPR-based endonucleases with...
Ch. 15.2 - Prob. 8LOCh. 15.2 - Prob. 1CCh. 15.2 - Prob. 2CCh. 15.2 - Prob. 3CCh. 15.3 - Prob. 9LOCh. 15.3 - Prob. 10LOCh. 15.3 - Discuss how qPCR, DNA microarrays (DNA chips), and...Ch. 15.3 - Explain how you would compare the expression of a...Ch. 15.3 - Prob. 2CCh. 15.4 - Describe how genome-wide association studies have...Ch. 15.4 - Explain how targeted gene silencing and knockout...Ch. 15.4 - Prob. 1CCh. 15.5 - Describe at least one important application of DNA...Ch. 15.5 - Prob. 1CCh. 15.5 - What are short tandem repeats (STRs), and why are...Ch. 15.5 - Why do gene targeting and mutagenesis screening in...Ch. 15.6 - Prob. 15LOCh. 15.6 - Prob. 16LOCh. 15.6 - Prob. 1CCh. 15.6 - Prob. 2CCh. 15.7 - Describe at least two safety issue associated with...Ch. 15.7 - What are some of the environment concerns...Ch. 15 - A plasmid (a) can be used as a DNA vector (b) is a...Ch. 15 - DNA molecules with complementary sticky ends...Ch. 15 - Prob. 3TYUCh. 15 - Which technique rapidly replicated specific DNA...Ch. 15 - Prob. 5TYUCh. 15 - A cDNA clone contains (a) introns (b) exons (c)...Ch. 15 - Prob. 7TYUCh. 15 - Gel electrophoresis separates nucleic acids on the...Ch. 15 - A CRISPR locus in a bacterium contains (a) short...Ch. 15 - DNA molecular with complementary sticky ends...Ch. 15 - These highly polymorphic molecular markers are...Ch. 15 - Prob. 12TYUCh. 15 - Prob. 13TYUCh. 15 - Prob. 14TYUCh. 15 - EVOLUTION LINK DNA technology, such as the...Ch. 15 - SCIENCE, TECHNOLOGY, AND SOCIETY What are some...
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- Humans and chimpanzees share about 98% of their DNA. What is DNA? What might be the role of regulatory genes in producing the anatomical differences between these two lineages? Give two examples of how the field of genetics has revolutionized biological science. What is polymerase chain reaction (PCR) and why is it important in genetics?arrow_forwardYou just graduated from college and started working at a biotech startup called Scrofabulous. Your first job assignment is to clone the pig gene for the hormone prolactin. Assume that the pig gene for prolactin has not yet been isolated, sequenced, or mapped; What would be the most useful and economical first step to go about identifying and cloning the pig gene for prolactin? use the amino acid sequence of mouse prolactin to design a pair of degenerate oligonucleotide PCR primers to PCR-amplify the pig prolactin gene. RNAseq the pituitary gland of the pig, the most abundant gene is likely to to be prolactin Conduct a proteome search for peptides that match parts of mouse prolactin protein Sequence the pig genome, then translate the genome to find the gene predicted to encode for prolactin Crystalize the mouse prolactin protein and use Google's DeepMind Al to find the closest amino acid sequence in the pig proteomearrow_forwardGive typing answer with explanation and conclusion If you want to identify genes linked to autism in a mouse model, which genetic approach or approaches could you use? (Mark all that apply) A) Reverse Genetics B) Forward Genetics C) Optogenetics D) Population Geneticsarrow_forward
- Do all of them True/False 31) The process by which an electrical charge is used to introduce DNA into a cell to produce a transgenic organism is called electroporation.Answer: 32) Reproductive cloning is used to produce large amounts of mammalian proteins from transgenic agricultural animals such as cattle.Answer: 33) In gene addition, homologous recombination is used to remove the original gene and replace it with the cloned gene.Answer: 34) All stem cells have the potential to differentiateAnswer: 35) A bone marrow transplant involves the transfer of multipotent stem cellsAnswer: 36) The fact that in mammalian systems multiple genes may compensate for the loss of a gene is called gene redundancy.Answer:arrow_forwardWooly Mammoths have been extinct for about 10,000 years; however, their remains have been well persevered in Siberia. Due to global warming, these remains are now available to be recovered. Scientists want to extract the DNA and through cloning insert the DNA into an elephant to clone the mammoth. What are some of the pros and cons of cloning an extinct animal?arrow_forwardIn a study showing that approximately 10% of protein-coding genes are essential for Cell survival .This translates into which of the following number of essential genes in the human genome .a)100 b) 500 c)1000 d)2000arrow_forward
- In 1995, the first free-living organism to have its genome completely sequenced was Haemophilus influenzae, a bacteria. In the following year, the baker’s yeast Saccharomyces cerevisiae was the first eukaryote genome sequence to be fully sequenced. The complete sequencing of the human genome and related organisms represent one of the greatest scientific achievements in the history of mankind.Elaborate on the importance of genome studies in general.arrow_forwardPlants are more readily manipulated by genetic engineeringthan are animals because(A) plant genes do not contain introns.(B) more vectors are available for transferring recombinantDNA into plant cells.(C) a somatic plant cell can often give rise to a completeplant.(D) plant cells have larger nucleiarrow_forwardHerbert Boyer and Stanley Cohen pioneered the technique of DNA cloning allowing genes to be transferred from another biological species easily. Their work also gave rise to the development of different recombinant proteins with therapeutic applications like insulin and growth hormone. The former was cloned using Escherichia coli. coli in 1978. With this breakthrough, the first licensed drug produced using recombinant DNAtechnology was human insulin, developed by Genentech, licensed and marketed by Eli Lilly in 1982. Scientists were able to identify and isolate the gene fragment or the gene of interest, in this case, the gene that is responsible for producing insulin. Moreover, they were able to isolate the bacterial DNA of E. coli. The plasmid and DNA fragment were cut using a restriction enzyme. This DNA fragment was inserted into the plasmid using a DNA ligase. When the DNA fragment was then placed into the bacterial DNA, it was then introduced to the host cell (E. coli) and was then…arrow_forward
- Because genetic engineering involves the modification of an organism's set of instructions, it has created a dilemma raising both moral and ethical concerns. For instance, a biotechnological company has found a way to produce rice that is immune to pests and diseases, which is vital for the establishment of food security. However, the methods that will be implemented are by splicing off the genes of endangered pandas using invasive procedures that may harm their population. Will you support this? Why or why not? Limit your answers to 5 sentences or less. Be brief and concise.arrow_forwardWhat are some possible research questions and practical applications that could be addressed by creating organisms with artificial chromosomes and synthetic genomes? What might be some potential safety, environmental, social, and ethical concerns about creating organisms with synthetic genomes?arrow_forwardModel organisms are those widely used by researchers who wish to understand basic processes that are common to many species. Bacteria such as Escherichia coli are model organisms for modern geneticists. Give three reasons why bacteria would be useful in genetic experiments.arrow_forward
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Mechanisms of Genetic Change or Evolution; Author: Scientist Cindy;https://www.youtube.com/watch?v=5FE8WvGzS4Q;License: Standard Youtube License