Essentials of Genetics
9th Edition
ISBN: 9781292108933
Author: KLUG
Publisher: PEARSON
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Chapter 15, Problem 20PDQ
Summary Introduction
To review:
In a regulated gene, the binding of transcription factors to its DNA (Deoxyribonucleic acid) recognition sequence is important and sufficient for the initiation of transcription.
Introduction:
The regulatory proteins that influence the transcription initiation by behaving as acting sites for promoters, enhancers, and silencers are considered as transcription factors. Transcription factors have multiple and complex effects on transcription. Some of the transcription factors can increase or some can decrease the levels of transcription.
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What are the role of transcription proteins? Explain briefly at your own words
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Chapter 15 Solutions
Essentials of Genetics
Ch. 15 -
CASE STUDY | A mysterious muscular dystrophy
A...Ch. 15 -
CASE STUDY |A mysterious muscular dystrophy
A...Ch. 15 -
CASE STUDY |A mysterious muscular dystrophy
A...Ch. 15 -
HOW DO WE KNOW?
1. In this chapter, we have...Ch. 15 -
2. Review the Chapter Concepts list on p. 280....Ch. 15 - Describe which enzymes are required for lactose...Ch. 15 - Contrast positive versus negative regulation of...Ch. 15 -
5. Both attenuation and riboswitches rely on...Ch. 15 - For the lac genotypes shown in the accompanying...Ch. 15 -
7. For the genotypes and conditions (lactose...
Ch. 15 -
8. The locations of numerous lacI– and lacIs...Ch. 15 - Explain why catabolite repression is used in...Ch. 15 - Describe experiments that would confirm whether or...Ch. 15 - Predict the level of genetic activity of the lac...Ch. 15 - Predict the effect on the inducibility of the lac...Ch. 15 -
13. Describe the role of attenuation in the...Ch. 15 -
14. In a theoretical operon, genes A, B, C, and D...Ch. 15 - A bacterial operon is responsible for production...Ch. 15 - A marine bacterium is isolated and is shown to...Ch. 15 -
17. Why is gene regulation more complex in a...Ch. 15 -
18. List and define the levels of eukaryotic gene...Ch. 15 -
19. Distinguish between the cis-acting regulatory...Ch. 15 - Prob. 20PDQCh. 15 - Compare the control of gene regulation in...Ch. 15 - Many eukaryotic promoter regions contain CAAT...Ch. 15 -
23. What is RNA-induced gene silencing in...Ch. 15 - Although it is customary to consider...Ch. 15 - DNA methylation is commonly associated with a...Ch. 15 - The interphase nucleus appears to be a highly...Ch. 15 - It has been estimated that at least two-thirds of...
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- Hydrogen bonds are important in DNA replication and transcription. They are relatively weak chemical bonds. Why is this a desirable feature for DNA? Describe the effect (s) of changing (mutating) the promoter on the transcription of the DNA strand/gene the promoter controls. What happens to protein synthesis if a nonsense codon is inserted into the gene? Explain why a point mutation does not necessarily change the original amino acid sequence. (Explain silent mutations) Choose any pentapeptide composed of five different amino acids. List the amino acids. Present one messenger RNA codon for each amino acids and the sequence of nucleotides on the DNA that originally coded for your pentapeptide.arrow_forward"After a sudden increase in transcription, a protein with a slow rate of degradation will reach a new steady state level more quickly than a protein with a rapid rate of degradation." is true or false.arrow_forwardDiscuss the three steps of Transcription (Initiation, Elongation, Termination).arrow_forward
- Describe the recognition process by which the tRNA for Nformylmethionine interacts with the portion of mRNA that specifies the start of transcription.arrow_forwardExplain Molecular Mechanisms of Transcription Repression and Activation.arrow_forwardExplain the ramifications to the process of transcription if spliceosomes excise exons and join the remaining introns togetherarrow_forward
- Define, explain, and differentiate between, the processes of transcription and translation. What enzymes or sub-cellular structures are responsible for carrying out these processes?arrow_forwardDetermine whether the following will increase or decrease gene expression: mRNA degradation mRNA capping Binding of a transcriptional activator Ubiquitination of a protein and targeting to the proteasomearrow_forwardDescribe the function and significance of ubiquitin and the proteasome in the regulation of gene expression.arrow_forward
- Why is it important for a transcription factor/activator to have a high affinity for a specific DNA sequence?arrow_forwardBriefly describe three stages of transcription. How is transcription initiated? How is transcription terminated?arrow_forwardIn 3-4 sentences eachExplain the difference between prokaryotic and eukaryotic transcription. Explain the difference between an activator and a repressor? Explain the difference between a promoter and an enhancer? Explain the difference between an intron and an exon? Explain what happens when eIF-2 is phosphorylated and when it is not phosphorylated?arrow_forward
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