Organic Chemistry
Organic Chemistry
10th Edition
ISBN: 9781259253379
Publisher: McGraw Hill Higher Education
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Chapter 15, Problem 29P
Interpretation Introduction

Interpretation:

The reactants obtained from the retrosynthesis of the target molecules are to be identified.

Concept introduction:

Reaction of formaldehyde with a Grignard reagent produces a primary alcohol.

Secondary alcohols are produced when Grignard reagent reacts with an aldehyde other than formaldehyde.

Tertiary alcohols are produced by the reaction of ketones with Grignard reagents.

If the alcohol is a secondary alcohol, then there are two possible disconnections during retrosynthesis.

If the alcohol is tertiary, there are three possible disconnections during retrosynthesis.

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