Gen Combo Ll Biology; Connect W/learnsmart Labs Access Card
4th Edition
ISBN: 9781259853197
Author: Robert Brooker
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 15.1, Problem 1EQ
Summary Introduction
To describe: The known effects of progesterone on oocytes prior to the study conducted by Masui and Markert.
Introduction: Yoshio Masui and Clement Markert studied the effect of progesterone on frog oocytes. Oocytes are the cells that on maturity turn into egg cells. Prior to their studies, a group of researchers has already identified that frog oocytes turn dormant in the G2 phase of cell cycle. Progesterone is the hormone produced by female frogs during mating season.
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Chapter 15 Solutions
Gen Combo Ll Biology; Connect W/learnsmart Labs Access Card
Ch. 15.1 - Researchers usually treat cells with drugs that...Ch. 15.1 - Which phases make up interphase?Ch. 15.1 - Prob. 1BCCh. 15.1 - Prob. 1EQCh. 15.1 - The Eukaryotic Cell Cycle CoreSKILL What...Ch. 15.1 - Prob. 3EQCh. 15.2 - Prob. 1CCCh. 15.2 - Prob. 2CCCh. 15.2 - Mitotic Cell Division Concept Check: What are the...Ch. 15.3 - Prob. 1CC
Ch. 15.3 - Sexual Reproduction Concept Check: What is the...Ch. 15.4 - Variation in Chromosome Structure and Number...Ch. 15 - Prob. 1TYCh. 15 - Prob. 2TYCh. 15 - Prob. 3TYCh. 15 - Prob. 4TYCh. 15 - Prob. 5TYCh. 15 - Which of the following is not an event of anaphase...Ch. 15 - Prob. 7TYCh. 15 - Which of the following statements accurately...Ch. 15 - Prob. 9TYCh. 15 - Aneuploidy may be the result of a. duplication of...Ch. 15 - Prob. 1CQCh. 15 - Prob. 2CQCh. 15 - Prob. 3CQCh. 15 - Prob. 1COQCh. 15 - A diploid eukaryotic cell has 10 chromosomes (5...
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- Explain why we can say that M-phase of the cell-cycle is triggered by a positive feedback loop. a) What would the consequences be if cohesins were working normally but condensins were not? and b) what stage of the cell cycle would this cause problems in? Why is it important for the centrosome to duplicate during G1-G2 (interphase) before M phase? The kinetochores serve as a link between the sister chromatids and the microtubules attached to the mitotic spindle. a) How are microtubules still able to exhibit dynamic instability after they are bound to the sister chromatids and b) why is this important to mitosis? As the name suggests, the Anaphase-promoting-complex (APC), promotes the 4th phase of mitosis by separating the sister chromatids so they can travel to separate poles of the cell, and prevents them from being re-zipped together. Describe how APC does these two things (Hint: one involves M-cyclin and the other involves…arrow_forwardWhat are the most important steps in cell-cycle regulation? Give some explanations and present some factors leading to uncontrolled cell cycle.arrow_forwardOne approach to studying the regulation of cell cycle progression (particularly in an era when genetic and molecular biology manipulations were less readily accomplished in mammalian cells) was to use treatments that induced cells to fuse and then monitor the behavior of the two nuclei in the resulting cell. The figure below depicts data from one such study. The investigators did preliminary work to produce populations of cells that were synchronized in various stages of the cell cycle (G1, S, or G2 in the examples shown below). They then fused the cells in different combinations and monitored subsequent events in each of the nuclei. For purposes of this question, we will pay particular attention to what occurred in the nucleus that came from the cell in G1. In one experiment (I), cells in the G1 and S phases were fused. That event caused the nucleus from the G1 cell to very quickly enter the S phase (sooner than it would otherwise have done so). In contrast, in a second experiment…arrow_forward
- One approach to studying the regulation of cell cycle progression (particularly in an era when genetic and molecular biology manipulations were less readily accomplished in mammalian cells) was to use treatments that induced cells to fuse and then monitor the behavior of the two nuclei in the resulting cell. The figure below depicts data from one such study. The investigators did preliminary work to produce populations of cells that were synchronized in various stages of the cell cycle (G1, S, or G2 in the examples shown below). They then fused the cells in different combinations and monitored subsequent events in each of the nuclei. For purposes of this question, we will pay particular attention to what occurred in the nucleus that came from the cell in G1. In one experiment (I), cells in the G1 and S phases were fused. That event caused the nucleus from the G1 cell to very quickly enter the S phase (sooner than it would otherwise have done so). In contrast, in a second experiment…arrow_forwardModify the diagram above to illustrate specific protein(s) that would participate in regulating this pathway if DNA damage was detected in these cells. What effect would this have on the progression of the cell cycle? If there is more than one possible outcome be sure to outline each one.arrow_forwardExplain the role of CDK inhibitors. If cyclin-CDK complexes are necessary to allow regulated progression through the eukaryotic cell cycle, what would be the physiological rationale for CDK inhibitors?arrow_forward
- Describe the likely consequences of bypassing the G1 and G2 checkpoints in the cell cycle. Why do compounds like nonylphenol lead to the multiplication of abnormal cells?arrow_forwardlook at the screenshot pleasearrow_forwardYou are studying the M-cyclin. You treat mitotic cells with an inhibitor of the proteasome and find that M-cyclin is no longer degraded and that this prolongs mitosis. You also find that in the presence of the inhibitor, M-cyclin is now running slower/larger in a Western than you have previously observed. In 1-2 sentences, explain why this might be happening. Edit View Insert Format Tools Table 12pt Paragraph B IU Αν S A C I AT²✓ #tv A MacBook Air X : Garrow_forward
- What are the three protein families that regulate the cell cycle? give an example for each:arrow_forwardA second hit might also occur through loss of heterozygosity (LOH). An example of how LOH may occur by reciprocal crossing over during mitosis is diagrammed in the figure attached. Discuss and interpret this model. Write a brief explanation of (a) what LOH means and (b) how LOH by mitotic reciprocal crossing over can give rise to a cell lineage with functional loss of the wild-type copy of a tumor suppressor gene.arrow_forwardIn Xenopus, one of the substrates of mitotic CDKs is the phosphatase Cdc25. When phosphorylated by mitotic CDKs, Cdc25 is activated. What is the substrate of Cdc25? How does this information help to explain the rapid rise in mitotic CDK activity as cells enter mitosis?arrow_forward
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