Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 15.1, Problem 1TQ
Summary Introduction
To review:
1. The enzymes that are used during the reverse reaction of the TCA (Tricarboxylic acid cycle) cycle and glycolysis.
2. Explain the reason behind the consumption of the same enzymes in both directions and the requirement of different enzymes in catabolic and anabolic directions.
Introduction:
The formation of complex
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Fructose can enter glycolysis by hexokinase. If fructose is used for glycolysis what enzyme can be skipped in glycolysis? And why can this enzyme be skipped if fructose is used for glycolysis?
What energetic barrier prevents glycolysis from simply running in reverse to synthesis glucose? What is the energetic cost to overcome this barrier?
Of the 36 molecules of ATP produced by the complete metabolism of glucose, how many are produced directly in glycolysis alone, that is, before the common pathway?
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Microbiology: An Evolving Science (Fourth Edition)
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- What is the key regulatory enzyme in glycolysis? Please explain how this enzyme is regulated just after a meal has been consumed.arrow_forwardhexokinase catalyzes the first reaction of the glycolysis pathway. What may happen if there is xylose in the reaction place? Briefly explain.arrow_forwardWhy is there such a large range of ∆G for the second step of glycolysis?arrow_forward
- Classify each enzyme of glycolysis into one of the six classes of enzymes. What class of enzymes has the most representatives in glycolysis? Why is this consistent with the goals of glycolysis? Why are ligases not represented in glycolysis?arrow_forwardDirect synthesis of ATP such as in step 5 of TCA and step 7 of glycolysis is known as?arrow_forwardGlucose is converted to pyruvate in glycolysis, yielding a netsynthesis of 2 ATP. In certain cells pyruvate can be reconverted to glucose during gluconeogenesis. How many ATPsare required to convert pyruvate back to glucose?arrow_forward
- Which reactions of glycolysis can be reversed? Which are irreversible? What is the significance of the metabolically irreversible reactions?arrow_forwardWhy isn’t the hexokinase step the commitment step for glycolysis even though it is the first step and is irreversible?arrow_forwardAt what point in glycolysis are all the reactions considered doubled?arrow_forward
- How many enyzymatic reactions are there in glycolysis pathway?arrow_forwardWhich generates more reducing power—glycolysis or the TCA cycle?arrow_forwarddraw in the structure of each metabolic intermediate in the glycolysis pathway in the figure above. In addition, fill in the missing enzymes from the picture above also, Which enzymes regulate glycolysis?arrow_forward
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