Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Textbook Question
Chapter 16, Problem 11P
In Genetic Analysis
Describe the crosses you would perform to determine the number of different genes represented by the
Based on your knowledge of the genetic tools for studying baker’s yeast, how would you clone the genes that are mutated in your respective yeast strains? What is an approach to cloning the human orthologs (see Genetic Analysis
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Chapter 16 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 16 - 14.1 What are the advantages and disadvantages of...Ch. 16 - Prob. 2PCh. 16 - 3. Genetic maps and physical maps are both...Ch. 16 - 14.5 What are the advantages and disadvantages of...Ch. 16 - 14.6 You have cloned the mouse ortholog (see...Ch. 16 - 14.13 The CBF genes of Arabidopsis are induced by...Ch. 16 - 14.14 When the S. cerevisiae genome was sequenced,...Ch. 16 - 14.15 Translational fusions between a protein of...Ch. 16 - In enhancer trapping experiments, a minimal...Ch. 16 - 14.19 In Genetic Analysis, we designed a screen to...
Ch. 16 - How would you design a genetic screen to find...Ch. 16 - 14.21 The eyes of Drosophila develop from imaginal...Ch. 16 - 14.22 Given your knowledge of the genetic tools...Ch. 16 - Mutations in the CFTR gene result in cystic...Ch. 16 - Prob. 16PCh. 16 - 14.25 How would you conduct a screen to identify...Ch. 16 - In land plants, there is an alternation of...Ch. 16 - 14.27 The Drosophila evenskipped (eve) gene is...Ch. 16 - Prob. 20PCh. 16 - 14.29 As shown in Figure, mutations in the...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A person with a rare genetic disease has a sample of her chromosomessubjected to in situ hybridization using a probe that is known to recognize band p11 on chromosome 7. Even though her chromosomes look cytologically normal, the probe does not bind to this person’s chromosomes. How would you explain these results? How would you use this information to positionally clone the gene that is related to this disease?arrow_forwardHow Does Yeast transformation experiments were used to identify the functional chromosomal elements necessary for normal chromosome replication and segregation?arrow_forwardIn Figure 17-25, which species is most closely related tothe ancestral yeast strain? Why are genes 3 and 13 referred to as duplicate?arrow_forward
- Do a few cells created by therapeutic cloning of your own somatic cells constitute life? If these cells do constitute life, do they have the same rights as a human being conceived naturally? If it were possible, should someone be allowed to grow his or her own therapeutic clone into an adult?arrow_forwardAntibiotics such as chloramphenicol, tetracycline, and erythromycin inhibit protein synthesis in bacteria, but have no effect on the synthesis of proteins encoded by eukaryotic nuclear genes. Cycloheximide inhibits the synthesis of proteins encoded by nuclear genes, but has no effect on bacterial protein synthesis. How might these compounds be used to determine which proteins are encoded by mitochondrial and chloroplast genomes?arrow_forwardWhat is inverse PCR? How are we going to use inverse PCR to help figure out the molecular location of the EP element on Drosophila melanogaster flies?arrow_forward
- Why are fruit flies considered a model genetic organism? Would humans fit this description?arrow_forwardFor each of the following scenarios, indicate Yes (it is cloning) or NO (it is NOT cloning) _____________________Sperm taken from a mole goat is combined with a female’s egg in a petri dish. The resulting embryo is implanted into the female’s uterus to develop. _____________________A sheep embryo, composed of 17 cells, is removed from the mother’s uterus and separated into individual cells. Each cell is allowed to multiply, creating 16 separate embryos, which are then implanted in different female sheep to develop to maturity. _____________________A cow with many desirable traits is stimulated with hormones to produce a number of egg cells. Each of these eggs is fertilized and implanted into a surrogate mother. _____________________In vitro fertilization _____________________Cell nuclei from an extinct wooly mammoth are placed into enucleated cow cells.arrow_forwardMutations in the CFTR gene result in cystic fibrosis in humans, a conditions in which abnormal secretions are present in the lungs, pancreas, and sweat glands. The gene was mapped to a 500-kb region on chromosome 7 containing 3 candidate genes. a)Using your knowledge of the disease symptoms, how would you distinguish between the candidate genes to decide which is most likely to encode the CFTR gene? b)How would you prove that your chosen candidate is the CFTR gene?arrow_forward
- In this module, you have learned about the use of balancer chromosomes (such as TM2 and TM6C in the below crossing scheme) for isolating Drosophila mutants during EMS mutagenesis. Please inspect the following crossing scheme and choose which of the following statements is correct. A. TM6C is preferable over TM2 when performing mutagenesis B. EMS induces chromosomal inversion C. A balancer chromosome helps to isolate on which chromosome the mutant is located D. Following the above crossing scheme all flies with no TM2 or TM6C markers are mutantsarrow_forwardwhy does a clone of cells produceonly one type of G-6-PD enzyme? What would you expect to happen if a clone was derived from an early embryonic cell? Whydoes the initial sample of tissue produce both forms of G-6-PD?arrow_forwardIn the reproductive cloning of an animal, what cell type is used as the source of the genome of the cloned animal? A sperm cell An egg cell Any gamete cell A somatic (non-gamete)) cellarrow_forward
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