Campbell Biology 11th Edition - Valuepack
Campbell Biology 11th Edition - Valuepack
11th Edition
ISBN: 9780134833545
Author: Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece Neil A. Campbell Lisa A. Urry
Publisher: PEARSON
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Chapter 17, Problem 11TYU

scientific inquiry Knowing that the genetic code is almost universal, a scientist uses molecular biological methods to insert the human β-globin gene (shown in Figure 17.12) into bacterial cells, hoping the cells will express it and synthesize functional β-globin protein. Instead, the protein produced is nonfunctional and is found to contain many fewer amino acids than does β-globin made by a eukaryotic cell. Explain why.

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. The genetic code is thought to have evolved to maximize genetic stability by minimizing the effect on protein function of most substitution muta- tions (single-base changes). We will use the six arginine codons to test this idea. Consider all of the substitutions that could affect all of the six arginine codons. (a) How many total mutations are possible? (b) How many of these mutations are "silent," in the sense that the mutant codon is changed to another Arg codon? (c) How many of these mutations are conservative, in the sense that an Arg codon is changed to a functionally similar Lys codon?

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Campbell Biology 11th Edition - Valuepack

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