BIO 102 General Biology II Updated Edition (Tidewater Community College)
BIO 102 General Biology II Updated Edition (Tidewater Community College)
3rd Edition
ISBN: 9781259614064
Author: Tidewater Community College
Publisher: MCG CUSTOM
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Chapter 17, Problem 16WIO

Mycobacterium tuberculosis causes most cases of tuberculosis. Strains of this bacterium that are resistant to all known antibiotics have become increasingly common. Explain how this change occurred; use the terms mutation, DNA, and natural selection in your answer.

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In 1918, an influenza pandemic that originated with avian flu killed 50 million people. Researchers isolated samples of that virus from bodies of infected people preserved in Alaskan permafrost since 1918. From the samples, they sequenced the viral genome, then reconstructed the virus. The reconstructed virus is 39,000 times more infectious than modern influenza strains, and 100 percent lethal in mice.   Understanding how this virus works can help us defend ourselves against other deadly influenza strains that arise. For example, discovering what makes it so infectious would help researchers design more effective vaccines. Critics of the research are concerned: If the virus escapes the containment facilities (even though it has not done so yet), it might cause another pandemic. Worse, terrorists could use the published DNA sequence and methods to make the virus for horrific purposes. Do you think this research makes us more or less safe?
Antibiotics such as tetracycline, streptomycin, and bacitracin are small organic molecules that are synthesized by particular species of bacteria. Microbiologists have hypothesized that the reason why certain bacteria make antibiotics is to kill other species that occupy the same environment. Bacteria that produce an antibiotic may be able to kill competing species. Eliminating competitors provides more resources for the antibiotic-producing bacteria. In addition, bacteria that have the genes necessary for antibiotic biosynthesis contain genes that confer resistance to the same antibiotic. For example, tetracycline is made by the soil bacterium Streptomyces aureofaciens. Besides the genes that are needed to make tetracycline, S. aureofaciens also has genes that confer tetracycline resistance; otherwise, it would kill itself when it makes tetracycline. In recent years, however, many other species of bacteria that do not synthesize tetracycline have acquired the genes that confer…
Scientists are concerned that bacteria will be resistant to all antibiotics within the next decade. Using your knowledge of genetics, briefly describe one method by which bacterial populations can develop drug resistance.  Do NOT use "mutation" as your answer.  Be more specific.  From what you learned in this chapter, how would the bacteria be able to change or mutate in order to become antibiotic resistant? Explain why the following statement is false: Sexual reproduction is the only mechanism for genetic change.  Do NOT use Mutation as your answer.  Be more specific:  what are other mechanisms by which microbes can change or mutate their DNA?

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BIO 102 General Biology II Updated Edition (Tidewater Community College)

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Bacterial Infections in Humans; Author: Professor Dave Explains;https://www.youtube.com/watch?v=FeFKAl9KyMg;License: Standard Youtube License