Concept explainers
(a)
Interpretation:
The synthesis of the given compound using the cyclopentanone as one of the reagents is to be suggested.
Concept introduction:
In aldol condensation, the
Answer to Problem 18.69P
The synthesis of the given compound using cyclopentanone as one of the reagents is:
Explanation of Solution
The given compound is:
The given compound is a
The precursor determined is cyclopentanone. Two molecules of cyclopentanone are used in the aldol condensation. Cyclopentanone, on reaction with a strong base, forms the given
The synthesis of the given compound is planned by identifying the precursor used with disconnection of
(b)
Interpretation:
The synthesis of the given compound using cyclopentanone as one of the reagents is to be suggested.
Concept introduction:
In aldol condensation, the aldehyde or ketone with
Answer to Problem 18.69P
The synthesis of the given compound using cyclopentanone as one of the reagents is:
Explanation of Solution
The given compound is:
The given compound is
The precursors determined are cyclopentanone and benzaldehyde. As the benzaldehyde has no
The synthesis of the given compound is planned by identifying the precursor used with disconnection of
(c)
Interpretation:
The synthesis of the given compound using cyclopentanone as one of the reagents is to be suggested.
Concept introduction:
In aldol condensation the aldehyde or ketone with
Answer to Problem 18.69P
The synthesis of the given compound using cyclopentanone as one of the reagents is:
Explanation of Solution
The given compound is:
The given compound is
The precursors determined are the cyclopentanone and acetophenone. As the both ketones has
The synthesis of the given compound is planned by identifying the precursor used with disconnection of
(d)
Interpretation:
The synthesis of the given compound using cyclopentanone as one of the reagents is to be suggested.
Concept introduction:
In aldol condensation the aldehyde or ketone with
Instead of carbonyl compounds, the compounds with polar
Answer to Problem 18.69P
The synthesis of the given compound using cyclopentanone as one of the reagents is:
Explanation of Solution
The given compound is:
The given compound is
The precursors determined are cyclopentanone and nitrile compound. As the nucleophile adds to carbonyl, the nucleophile can be produced by the reaction of one of the nitrile with a strong base like hydroxide. The nucleophile then reacts with ketone and produces the given
The synthesis of the given compound is planned by identifying the precursor used with disconnection of
(e)
Interpretation:
The synthesis of the given compound using cyclopentanone as one of the reagents is to be suggested.
Concept introduction:
The Robinson annulations reaction is the addition of enolate to conjugated carbonyl followed by intramolecular aldol condensation. One of the reactant in Robinson annulations must be
Answer to Problem 18.69P
The synthesis of given compound using cyclopentanone as one of the reagents is:
Explanation of Solution
The given compound is:
The given compound is
To get the precursor
The precursors determined are the cyclopentanone and
The synthesis of given compound is planned by identifying the precursor used with disconnection of
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Chapter 18 Solutions
EBK GET READY FOR ORGANIC CHEMISTRY
- (SYN) Show how to carry out each of the following syntheses, using any reagents necessary. Hint: In each case, the carbonyl group of a ketone or aldehyde is entirely removed. (a) (b) ? OCH3 OCH3 OCH3 OCH3 (c) (d) ? ? OH Pharrow_forward(SYN) Suggest how you would synthesize each of the following compounds beginning with pentan-2-one. (а) OH OH (b) ОН (c) OHarrow_forward(SYN) Show how to synthesize each of the following trisubstituted benzenes from a disubstituted benzenearrow_forward
- (SYN) Show how each of the following compounds can be synthesized from an acid chloride and either water, an alcohol, or an amine. For each reaction, provide the complete, detailed mechanism.arrow_forward(SYN) Show how to carry out each of the following transformations. (a) (b) ? ? (c) (d) ? ? CI HOarrow_forward(SYN) Show how each of the following alkyllithium reagents can be synthesized from an alkyl, alkenyl, alkynyl, or aryl halide. (a) (b) (c) Li (d) Li Li `Liarrow_forward
- Please answer very soon will give rating surelyarrow_forward(SYN) Show how you would synthesize each of these compounds from benzene.arrow_forward(SYN) Stilbene is used in the manufacture of dyes and also has estrogenic activity. Show how to synthesize stilbene using benzene and any carboxylic acid as your only sources of carbonarrow_forward
- ) (SYN) Show how each of the following lithium dialkylcuprate reagents can be synthesized from an alkyl, alkenyl, alkynyl, or aryl halide. (a) (b) (c) (d) CULI CuLi CuLi CuLiarrow_forwardHelp please, explain in detail. Thank you!arrow_forward(SYN) How would you synthesize the compound shown here using phenylethanal as your only source of carbon atoms? You may ignore stereochemistry.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning