Concept explainers
The cl gene that encodes the λ repressor has two promoters designated
a.
b.
c.
d.
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Chapter 18 Solutions
Genetics: Analysis and Principles
- What is the role of a substrate that controls a repressible operon? a. increase the production of inactive repressor proteins b. bind to the repressor protein and activate it c. bind to the repressor protein and deactivate it d. bind to the promoter region and decrease the affinity of RNA polymerase for the promoterarrow_forwardE. coli are grown on a medium containing lactose. Once glucose is added to the medium, the bacteria stop fermenting lactose. Which of the following BEST explains the observed effect? A. Cellular levels of cAMP are lowB.Glucose is bound to the promoter C. Repressor protein is bound to the operator D. Repressor protein is bound to the promoterarrow_forwardWhich of the following is true of transcription factors? A)The same transcription factors are found in all cell types. B)They can increase or decrease gene expression. C)They are a type of cis-acting element. D)They bind only to promoters.arrow_forward
- A temperature-sensitive mutant allele of Ras causes the Ras protein to be fixed in the GDP-bound state at the nonpermissive temperature. What phenotype would you expect a cell homozygous for this mutation to have at the nonpermissive temperature? A.) It would stop dividing. B.) It would divide continuously. C.) It would divide normally.arrow_forwardThe regulator protein that acts on a negative repressible operon is synthesized as a. an active activator. c. an active repressor. b. an inactive activator. d. an inactive repressor.arrow_forwardA particular strain of λ (lambda) can lysogenize its E. coli host at 30°C, but not at 42°C. Could a temperature-sensitive mutation in the int (integrase) gene explain this phenotype? A. There is insufficient information to answer the question. B. No C. Yesarrow_forward
- In the trp operon, if a mutation occurred in the gene for the repressor so that it could bind to the operator even in the absence of tryptophan____________. a) the inducer cannot bind trpO, so operon gene transcription occurs b) the active repressor cannot bind trpO, so operon gene transcription is attenuated c)the active repressor binds tpO, so operon gene transcription is always repressed d) the repressor binds the corepressor, and operon gene transcription occurs.arrow_forwardIn the trp operon, what happens to the trp repressor in the absence of tryptophan? a. It binds to the operator and represses transcription. b. It cannot bind to the operator, and transcription takes place. c. It binds to the regulator gene and represses transcription. d. It cannot bind to the regulator gene, and transcription takes place.arrow_forwardEukaryotic cells have multiple complex mechanisms for the regulation of gene expression, but a regulatory mechanism they rarely (if ever) use is a. operons. b. regulatory proteins. c. transcriptional factors. d. promoters.arrow_forward
- You are growing E. coli in a laboratory in order to study their operons. The growth media you are using contains lactose, no glucose and no tryptophan. Using your knowledge of operons and their regulation a.Which operons would be functional under these conditions? b.What repressors would be made? (NOTE: name the repressors using their gene names) c.Which repressor(s) would be made in the inactive form? d.Which repressor(s) would be made in the active form? e.Which repressor(s) under these conditions can bind the operator sequence? f.Which repressor(s)under these conditions cannot bind the operator sequence?arrow_forwardPlease choose the correct answer. The prokaryotic operator gene is turned on if a. a repressor binds with an aporepressor. b. an inducer binds with the operator gene. c. a repressor binds with a regulatory protein. d. an inducer binds with the regulatory protein.arrow_forwardCan one transcription factor sometimes act as a repressor and sometimes act as an activator? a. Yes, but it depends on where the transcription factor binds in the promoter b. Yes, but it depends on other proteins that might act with the transcription factor c. No, transcription factors are always either activators or repressors d. Yes, but only if a mutation happensarrow_forward
- Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning