To discuss:
The cause and mechanism of transfusion reactions and the reasons that lead to renal failure and death, and also to explain the terms agglutination and hemolysis.
Introduction:
Blood transfusion incompatibility can be fatal, and therefore, knowledge of both donor and recipient blood types is essential. The ABO blood typing system defines the various blood types based in the presence or absence of antigens. The antibodies are proteins, secreted by the plasma cells and are circulated in the plasma, and the ABO type antigens are glycolipids that are expressed on the surface of RBCs. Antibodies, by binding to antigens, label the antigens for destruction as a part of the body’s immune response.
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Anatomy & Physiology: The Unity of Form and Function
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