Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 19, Problem 10P
Summary Introduction

To explain: The way in which the αIIbβ3 integrin is held in its inactive state.

Concept introduction: Integrins are transmembrane adhesion proteins that are present as anchoring junctions between cell and the matrix as actin-linked cell–matrix junction. The affinity of these integrins is possible to modify if their cytoplasmic domains are altered, a process called as inside-out signaling.

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